| Cat.No. | Name | Information |
|---|---|---|
| M5929 | Prostaglandin E2 | Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor. |
| M10827 | GSK726701A | GSK726701A is a partial agonist of prostaglandin E2 receptor 4 (EP4),pEC50is 7.4. |
| M10807 | CJ-42794 | CJ-42794 is a selective prostaglandin receptor EP4 antagonist that inhibits [3H]-PGE2 binding to EP4 receptors with an average pKi of 8.5 and is more than 200 times more selective than EP1, EP2 and EP3. |
| M10795 | BGC-20-1531 free base | BGC-20-1531 (PGN 1531) free base is a potent selective prostaglandin EP4 receptor antagonists, pKB The value is 7.6. BGC-20-1531 free base has the potential to study migraines. |
| M10791 | BAY-1316957 | BAY-1316957 is a potent, selective, orally active antagonist of the prostaglandin E2 receptor subtype 4 (EP4-R) against human EP4-R IC50 15.3 nM. BAY-1316957 has excellent drug metabolism and pharmacokinetic properties and can be used in the study of endometriosis. |
| M6876 | L-161982 | L-161982 is a EP4 receptor antagonist that is selective over all other members of the prostanoid receptor family (Ki values are 0.024, 0.71, 1.90, 5.10, 5.63, 6.74, 19 and 23 μM for human EP4, TP, EP3, DP, FP, IP, EP1 and EP2 receptors respectively). L-161982 completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. |
| M6821 | Iloprost | Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. |
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