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Iloprost

Cat. No. M6821

All AbMole products are for research use only, cannot be used for human consumption.

Iloprost Structure
Synonym:

Ciloprost; ZK 36374

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Quality Control & Documentation
Biological Activity

Iloprost is a prostacyclin (PGI2) analog that binds with high affinity to IP, EP1 and EP3 receptors (Ki values are 11, 11, 56, 284, 619, 1035, 1870 and 6487 nM for IP, EP1, EP3, EP4, FP, DP, EP2 and TP receptors respectively). Iloprost inhibits platelet aggregation induced by collagen, thrombin and ADP (IC50 values are 0.24, 0.71 and 1.07 nM respectively).

Chemical Information
Molecular Weight 360.49
Formula C22H32O4
CAS Number 78919-13-8
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Eltze, et al. Mol Pharmacol. Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.

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  Catalog
Abmole Inhibitor Catalog




Keywords: Iloprost, Ciloprost; ZK 36374 supplier, Prostaglandin Receptor, inhibitors, activators

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