| Cat.No. | Name | Information |
|---|---|---|
| M5929 | Prostaglandin E2 | Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor. |
| M10180 | GW627368X | GW627368X is a novel, potent and selective competitive antagonist of prostanoid EP4 receptors with additional human TP receptor affinity. |
| M9854 | Taprenepag | Taprenepag (CP-544326) is a potent selective prostagenin EP(2) agonist with IC50 of 10 and 15 nM for human and rat EP2, respectively. Taprenepag has higher selectivity for EP2 than other EP receptors (IC50>3200 nM for EP1, EP3 and EP4) and a group of 37 G-protein-coupled receptors. |
| M9776 | Darbufelone | Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production, it is also a COX-2 inhibitor potentially for the treatment of rheumatoid arthritis. |
| M9473 | RO1138452 | RO1138452 is a potent and selective antagonist for both human and rat IP receptors and that is possesses analgesic and anti-inflammatory potential. |
| M9464 | Asapiprant | Asapiprant is a potent and selective DP1 receptor antagonist, with a Ki of 0.44 nM. |
| M9446 | Dazoxiben hydrochloride | Dazoxiben hydrochloride is a potent, orally active thromboxane (TX) synthase inhibitor that reduces the formation of blood clots. |
| M9277 | TG4-155 | TG4-155 is a brain penetrant prostaglandin EP2 specific antagonist, with a Ki of 9.9 nM. |
| M9232 | PF-04418948 | PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. |
| M8973 | Fevipiprant | Fevipiprant (QAW039) is a selective, potent, reversible competitive CRTh2 antagonist. |
| M8971 | Grapiprant | Grapiprant is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. |
| M8780 | ONO-AE3-208 | ONO-AE3-208 is an orally active prostaglandin E2 receptor 4 (EP4)-selective antagonist (Ki in nM = 1. |
| M7428 | Treprostinil | Treprostinil (UT-15) is a potent prostacyclin (PGI 2) analog. |
| M7426 | Travoprost | Travoprost is a potent and selective FP prostaglandin receptor agonist. |
| M7385 | TCS 2510 | TCS 2510 is a selective EP4 agonist. |
| M6714 | Epoprostenol sodium | Epoprostenol is an endogenous steroid and a selective agonist of the prostaglandin I2 receptor (PI2R) that inhibits platelet aggregation and induces vasodilation. It can be used in studies related to pulmonary hypertension. |
| M6669 | DG-041 | DG-041 is a potent and selective EP3 antagonist; antiplatelet and antithrombotic. DG-041 inhibits PGE2 facilitation of platelet aggregation. DG-041 crosses the blood-brain barrier. |
| M6138 | E-7046 | E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities. |
| M5955 | Seratrodast | Seratrodast(AA 2414) is a potent and selective thromboxane A2 receptor (TP) antagonist. |
| M5918 | Ramatroban | Ramatroban (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. |
| M5846 | Ozagrel HCl | Ozagrel HCl is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. |
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