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Prostaglandin Receptor Prostaglandin Receptor

Cat.No.  Name Information
M5929 Prostaglandin E2 Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor.
M5729 Latanoprost Latanoprost is a prostaglandin F2α analog as well as a prostaglandin-like selective FP receptor agonist with lipophilic and corneal penetrating properties. In addition, Latanoprost also increases ocular fluid outflow, thereby reducing intraocular pressure, and may be used in studies related to glaucoma.
M5401 Prostaglandin E1 (Alprostadil) Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, which induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases.
M3951 Terutroban Terutroban is a selective antagonist of the thromboxane receptor.
M3881 Tafluprost Tafluprost is a fluorinated analog of prostaglandin F2-alpha and a PGF2alpha agonist that may be used in glaucoma-related studies.
M2689 Ethamsylate Ethamsylate is a haemostatic compound, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.
M58167 Tafluprost acid Tafluprost acid (AFP-172) is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor (IC50=67 nM) than for the prostanoid FP receptor.
M56317 TG8-260  TG8-260 is a second-generation EP2 antagonist developed to alleviate the pathology of central nervous system and peripheral diseases driven by inflammation.
M56316 Camonagrel  Camonagrel is a compound that has inhibitory effects on Prostaglandin E2.
M56315 BAY 73-1449  BAY 73-1449 is a selective antagonist of prostacyclin receptor (IP), with high potency (IC50 of less than 0.1 nM) in cAMP assays in Human HEL cells and rat DRG.
M56314 AZ12672857  AZ12672857 is an orally active inhibitor of EphB4 (IC50=1.3 nM) and Src kinases.
M56313 Latanoprost lactone diol Latanoprost lactone diol is an intermediate in the synthesis of Latanoprost.
M56312 15-keto-Prostaglandin F2a 15-keto-Prostaglandin F2α (15-keto-PGF2α) is a metabolite of Prostaglandin F2α.
M56311 11-Deoxy Prostaglandin E2  11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM.
M56310 BGC-20-1531 hydrochloride BGC 20-1531 (PGN 1531) hydrochloride is a potent and selective prostanoid EP4 receptor antagonist, with a pKb of 7.6.
M56309 13,14-Dihydro-15-keto prostaglandin D2 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway.
M50157 DT-9081 DT-9081 is a potentially best-in-class, orally active, small molecule prostaglandin EP4 receptor antagonist that reverses prostaglandin E2 (PGE2)-induced immunosuppression in certain tumors by blocking the EP4 receptor present on immune cells.
M43878 Unoprostone Unoprostone is a prostaglandin F2α analog (PGAs) that reduces oxidative stress and light-induced retinal cell death as well as phagocytosis dysfunction by activating BK channels. It can be used in studies related to glaucoma or hypertension.
M41911 Prostaglandin B1 Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin E1.
M41910 EP3 antagonist 4 EP3 antagonist 4 is an EP3 antagonist, with a Ki value of 2 nM for hEP.
M41909 Vorbipiprant Vorbipiprant (CR6086) is an EP4 receptor antagonist, serving as a targeted immunomodulator.




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