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Unoprostone

Cat. No. M43878

All AbMole products are for research use only, cannot be used for human consumption.

Unoprostone Structure

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Quality Control & Documentation
Biological Activity

Unoprostone is a prostaglandin F2α analog (PGAs) that reduces oxidative stress and light-induced retinal cell death as well as phagocytosis dysfunction by activating BK channels. It can be used in studies related to glaucoma or hypertension.

Chemical Information
Molecular Weight 382.53
Formula C22H38O5
CAS Number 120373-36-6
Solubility (25°C) DMF 25 mg/mL
DMSO 17 mg/mL
Ethanol 12 mg/mL
Storage -20°C
References

[1] Ling Yu, et al. Biochim Biophys Acta. Unoprostone activation of BK (KCa1.1) channel splice variants

[2] Nathan V Harms, et al. Expert Opin Pharmacother. Current status of unoprostone for the management of glaucoma and the future of its use in the treatment of retinal disease

[3] Paulo Augusto de Arruda Mello, et al. Drug Saf. Safety of unoprostone isopropyl as mono- or adjunctive therapy in patients with primary open-angle glaucoma or ocular hypertension

[4] M Haria, et al. Drugs Aging. Unoprostone (isopropyl unoprostone)

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Keywords: Unoprostone supplier, Prostaglandin Receptor, inhibitors, activators

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