Catalog

PKA Proteinkinase A

Inhibitors

Cat.No.	Name	Information
M9782	Bucladesine calcium	Bucladesine calcium is a cell-permeable cyclic AMP (cAMP) analog and selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP.
M8923	CCG215022	CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50 values of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively.
M3559	H-89	H-89 is a potent PKA inhibitor with K_i of 48 nM, 10-fold selective for PKA than PKG, greater than 500-fold selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II.
M2475	Bucladesine Sodium Salt	Bucladesine, a membrane permeable selective activator of PKA, has a critical role in up-regulation of ChAT and VAChT gene expression in PC12 cells by activation of extracellular signal regulated kinase (ERK) in Ca²⁺- and PKA-dependent manner.
M1729	H-89 Dihydrochloride	H-89 dihydrochloride is a selective inhibitor of protein kinase A (PKA) with an IC50 value of 135 nM.
M1593	8-Bromo-cAMP	8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator.