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Bucladesine, a membrane permeable selective activator of PKA, has a critical role in up-regulation of ChAT and VAChT gene expression in PC12 cells by activation of extracellular signal regulated kinase (ERK) in Ca2+- and PKA-dependent manner.
Arch Dermatol Res. 2012 May;304(4):313-7.
The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo-adenosine monophosphate (bucladesine), is active in a model of acute skin inflammation
Bucladesine Sodium Salt purchased from AbMole
Molecular Weight | 492.38 |
Formula | C18H24N5O8P.Na |
CAS Number | 16980-89-5 |
Solubility (25°C) | Water ≥ 34 mg/mL DMSO ≥ 30 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] G Wolf. Release of stored retinol from adipocytes
[5] F H Epstein, et al. Na-K-Cl cotransport in chloride-transporting epithelia
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Products are for research use only. Not for human use. We do not sell to patients.
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