All AbMole products are for research use only, cannot be used for human consumption.
Bucladesine, a membrane permeable selective activator of PKA, has a critical role in up-regulation of ChAT and VAChT gene expression in PC12 cells by activation of extracellular signal regulated kinase (ERK) in Ca2+- and PKA-dependent manner.
Arch Dermatol Res. 2012 May;304(4):313-7.
The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo-adenosine monophosphate (bucladesine), is active in a model of acute skin inflammation
Bucladesine Sodium Salt purchased from AbMole
| Molecular Weight | 492.38 |
| Formula | C18H24N5O8P.Na |
| CAS Number | 16980-89-5 |
| Solubility (25°C) | Water ≥ 34 mg/mL DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] G Wolf. Release of stored retinol from adipocytes
[5] F H Epstein, et al. Na-K-Cl cotransport in chloride-transporting epithelia
| Related PKA Products |
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CW 008 is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice. |
| Malantide
Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. |
| PKI (14-24)amide TFA
PKI (14-24)amide TFA is a potent PKA inhibitor. |
| PKA Inhibitor Fragment (6-22) amide
PKA Inhibitor Fragment (6-22) amide is an inhibitor of cAMP-dependent protein kinase A (PKA), with a Ki of 2.8 nM. |
| PKI (14-24)amide
PKI (14-24)amide is a potent PKA inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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