| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M3111 | Uracil | Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for compound delivery and as a pharmaceutical. |
| M3093 | Troxipide | Troxipide is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum. |
| M3080 | Tolperisone hydrochloride | Tolperisone hydrochloride is an ion channel blocker and centrally-acting muscle relaxant. |
| M3075 | Tolazamide | Tolazamide is a sulfonylurea anti-diabetes compound that causes the pancreas to release insulin, which helps lower blood sugar. |
| M3042 | Suxibuzone | A precursor compound of phenylbutanone, a nonsteroidal anti-inflammatory compound, commonly used in horses. |
| M3023 | Sodium Picosulfate | Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion. |
| M2970 | Pyridoxine hydrochloride | Pyridoxine hydrochloride is a form of vitamin B6. |
| M2955 | Pramoxine hydrochloride | Pramoxine is a topical local anesthetic that has been shown to have antipruritic properties. |
| M2896 | OAC1 | OAC1 (Oct4-activating compound 1) is a potent Oct4 activator that activates both the Oct4 and Nanog promoters, promotes induced multifunctional stem cell (iPSC) formation, and activates OCT4 through upregulation of HOXB4 expression.Additionally, OAC1 increases the transcription of the Oct4-Nanog-Sox2 triplet and TET1 and promotes cell reprogramming by increasing efficiency and shortening reprogramming time. and TET1 transcription, and may promote cell reprogramming by increasing efficiency and shortening reprogramming time. |
| M2890 | NSC 632839 | NSC 632839 is not only a DUB inhibitor, but also a deSUMOylase inhibitor, it inhibits USP2, USP7, and SENP2 with IC50 of 45 μM, 37 μM, and 9.8 μM, respectively. |
| M2870 | MSDC-0160 | MSDC 0160 (Mitoglitazone) is an insulin sensitizer that regulates the mitochondrial target of thiazolidinedione (mTOT) and a regulator of mitochondrial pyruvate vector (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has potential for use in Alzheimer's disease. |
| M2864 | Moguisteine | Moguisteine is a novel peripheral non-narcotic antitussive compound. |
| M2846 | Mevastatin | Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself. |
| M2839 | Mequinol | Mequinol (4-Methoxyphenol) is a depigmentation agent. |
| M2832 | Mechlorethamine hydrochloride | Mechlorethamine is the prototype of alkylating agents, it works by binding to DNA, crosslinking two strands and preventing cell duplication. |
| M2803 | L-Arginine hydrochloride | L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. |
| M2800 | KY02111 | KY02111 is a widely used small molecule that boosts cardiomyogenesis. Chemical genetics of KY02111 identified squalene synthase (SQS) as a molecular target of KY02111. By disrupting the interaction of SQS with cardiac ER-membrane protein TMEM43, KY02111 impairs TGFβ/SMAD signaling and recapitulates the clinical mutation of TMEM43 that causes an inherited heart disease. |
| M2780 | Isovaleramide | Isovaleramide is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases. |
| M2773 | Iopromide | Iopromide is a water soluble, hydrophilic and nonionic iodinated contrast agent for x-ray imaging. |
| M2771 | Imipramine hydrochloride | Imipramine is a tricyclic antidepressant (TCA) of the dibenzazepine group, mainly used in the treatment of major depression and enuresis (inability to control urination). |
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