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Euphorbia Factor L1, a diterpenoid compound, can reduce the protein and mRNA levels of Bcl-2, PI3K, AKT and mTOR, and up-regulate the protein levels of Caspase-9 and Caspase-3. There was no effect on caspase-9 and caspase-3 protease. Euphorbia Factor L1 can induce autophagy and has anti-cancer, anti-adipogenesis, anti-osteoclast formation and multiple drug resistance regulation effects.
| CAS Number | 76376-43-7 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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