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Dihydroberberine inhibited the human Ether-related gene (hERG) channel and significantly reduced the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine has anti-inflammatory, antiatherosclerotic, hylipidemic and antitumor activities.
| Molecular Weight | 337.36 |
| Formula | C20H19NO4 |
| CAS Number | 483-15-8 |
| Solubility (25°C) | Water ≥ 6 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Xintong Zhang, et al. The influence of the gut microbiota on the bioavailability of oral drugs
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