| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8380 | ML 210 | Ml-210 is a selective, covalent glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 30 nM. Ml-210 binds GPX4 selenocysteine residues. ML210 has anticancer activity and has shown cytotoxic effects on melanoma, lung adenocarcinoma, fibrosarcoma and pancreatic cancer cell lines. |
| M8372 | Tienilic Acid | Tienilic Acid (Ticrynafen) is a P450 inhibitor, a specific suicide substrate for CYP2C9 and CYP2C10. |
| M8371 | 9(S)-HODE | 9(S)-HODE is produced by the lipoxygenation of linoleic acid. |
| M8351 | PH-002 | PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that restores mitochondrial cytochrome c oxidase subunit 1 levels, rescues impairments of mitochondrial motility and neurite outgrowth. |
| M8345 | ML239 | ML239 is an inhibitor of breast cancer stem cells found from a screen using stem cell-like human mammary epithelial cells (HMLE). |
| M8323 | Dexpramipexole dihydrochloride | Dexpramipexole dihydrochloride (R-(+)-Pramipexole) is a neuroprotective agent; weak non-ergoline dopamine agonist. |
| M8306 | NPS2143 hydrochloride | NPS2143 is a selective calcium-sensing receptor (CaR) antagonist. |
| M8293 | GTS-21 | GTS-21 is a selective agonist at α-7 nicotinic receptors with anti-inflammatory and cognition enhancing activities. |
| M8284 | Carbazeran | Carbazeran is an Aldehyde oxidase (AO) substrate and a phosphodiesterase inhibitor that produces concentration-dependent positive inotropic responses. |
| M8264 | CDPPB | Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. |
| M8262 | HI-6 | HI-6 is an efficient oxime cholinesterase reactivator that is used as an antidote for organophosphates (Ops) exposure. |
| M8231 | Perhexiline maleate salt | Perhexiline maleate is an anti-anginal metabolic modulator. |
| M8222 | Acenocoumarol | Acenocoumarol is a warfarin analog, an anticoagulant that inhibits Vitamin K epoxide reductase. |
| M8221 | Trapidil | Terapidil is an antiplatelet compound that partially acts as a competitive inhibitor of phosphodiesterase inhibitors and platelet-derived growth factor (PDGF) receptors. |
| M8217 | BLT-1 | Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. |
| M8201 | Sesamin | Non-competitive Δ5-desaturase inhibitor. |
| M8187 | SB 657510 | SB 657510 slows development of diabetes-associated atherosclerosis in mouse model of diabetes. |
| M8164 | Stauprimide | Stauprimide is an enhancer stem cell differentiation into endoderm. |
| M8159 | STX64 | STX64 is a potent, irreversible inhibitor of steroid sulfatase. |
| M8151 | SR-95531 | SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities. |
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