| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8729 | Syrosingopine | Syrosingopine is an antihypertensive agent related to reserpine that was found to potentiate the anticancer effects of the antidiabetic agent metformin and phenformin without harmful effects on normal cells. |
| M8725 | SR144528 | SR144528 is a potent and highly selective cannabinoid CB2 receptor inverse agonist. |
| M8694 | K-604 | K-604 inhibits against acyl-coenzyme A (acyl-CoA):cholesterol O-acyltransferase-1 (ACAT1, SOAT1) activitiy in a selective (IC50 = 450 nM vs. |
| M8691 | DDR1 Inhibitor 7rh | DDR1 Inhibitor 7rh is an orally available, potent, ATP-competitive DDR1-selective inhibitor with in vitro and in vivo anti-cancer efficacy. |
| M8673 | MS0015203 | MS0015203 is a potent and selective agonist of the neuropeptide receptor GPR171. |
| M8653 | BAM15 | BAM15 is a cell penetrant and potent uncoupler of oxidative phosphorylation in mitochondria that that does not depolarizes the plasma membrane. |
| M8630 | BRD4354 | BRD4354 is a zinc chelating, reversible inhibitor of zinc-dependent histone deacetylases with selectivity for HDAC5 and HDAC9. |
| M8625 | OGG1 Inhibitor O8 | OGG1 Inhibitor O8 is a potent inhibitor of 8-Oxoguanine DNA Glycosylase-1 (OGG1), part of the DNA base excision repair (BER) pathway. |
| M8620 | AS8351 | AS8351 is an iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B), a histone H3K4 demethylase involved in regulation of cell proliferation and stem cell self-renewal and differentiation. |
| M8613 | CDN1163 | CDN1163 is an allosteric activator of sarco/ endoplasmic reticulum Ca2+-ATPase (SERCA) that potently lowered fasting blood glucose, improved glucose tolerance and ameliorated hepatosteatosis in ob/ob mice. |
| M8576 | LP-211 | LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor with a Ki value of 0. |
| M8575 | Tipiracil hydrochloride | Tipiracil is an inhibitor of thymidine phosphorylase. |
| M8571 | VPC-14228 | VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR) that binds to AR DNA-binding domain (AR DBD). |
| M8545 | PACA | PACA is a potentiator of NGF-induced neurite outgrowth that attenuates 6-hydroxydopamine (6-OHDA) neurotoxicity in dopaminergic PC12 cells. |
| M8523 | ACT-462206 | ACT-462206 is a orally active, brain penetrant, potent and selective dual orexin1/2 receptor antagonist (DORA). |
| M8521 | Farrerol | Farrerol is major bioactive component from Rhododendron dauricum L. |
| M8493 | NSC756093 | NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction that inhibits proliferation of paclitaxel resistant cancer cells. |
| M8486 | BRD7552 | BRD7552 is a potent inducer of pancreatic and duodenal homeobox 1 (PDX1) transcription factor that enhanced insulin expression. |
| M8452 | ELN484228 | ELN484228 is a cell penetrant α-synuclein ligand that rescues of α-synuclein induced disruption of vesicle trafficking and dopaminergic neuronal loss and neurite retraction. |
| M8382 | kb-NB142-70 | kb-NB142-70 is a derivative of the PKD1 inhibitor CID755673, with approximately 6-fold greater potency (IC50 for inhibition of PKD1 = 28. |
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