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Mildronate

Cat. No. M14730

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Mildronate Structure
Synonym:

Meldonium; MET-88; Quaterin

Size Price Availability Quantity
100mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Mildronate (Meldonium) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes.

Chemical Information
Molecular Weight 146.19
CAS Number 76144-81-5
Solubility (25°C) Water 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Artem P Gureev, et al. Mildronate protects heart mtDNA from oxidative stress toxicity induced by exhaustive physical exercise

[2] Dilan Demir, et al. Neuroprotective effects of mildronate in a rat model of traumatic brain injury

[3] Vija Klusa, et al. Mildronate and its neuroregulatory mechanisms: targeting the mitochondria, neuroinflammation, and protein expression

[4] Nikolajs Sjakste, et al. Mildronate: an antiischemic drug for neurological indications

[5] Maija Dambrova, et al. Mildronate: cardioprotective action through carnitine-lowering effect

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Keywords: Mildronate, Meldonium; MET-88; Quaterin supplier, inhibitors, activators

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