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LPL Receptor Lysophospholipid receptor


Cat.No.  Name Information
M21207 BMS-986278 BMS-986278 is a potent LPA1 antagonist with a Kb of 6.9 nM.
M21193 SAR247799 The S1P1 agonist SAR247799 is a biased agonist of the S1P1 sphingosine receptor, preferentially activating G protein signaling over the β-arrestin and internalization pathways.
M21147 GLPG2938 GLPG2938 is a potent and selective S1P2 antagonist.GLPG2938 can be used in the study of idiopathic pulmonary fibrosis (IPF).
M14002 LPA2 antagonist 1 LPA2 antagonist 1 is a LPA2 antagonist with an IC50 of 17 nM.
M14001 FTY720 (S)-Phosphate FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury.
M14000 Fingolimod Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.
M13999 BMS-986020 sodium BMS-986020 sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist.
M13998 ASP-4058 ASP-4058 is a next-generation, selective and oral bioactive agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5), ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile.
M11160 1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl Lysophosphatidic acid (1-Oleoyl-Sn-glycero-3-phosphate) sodium is an effective bioactive phospholipid, which is an LPA receptor activator. 1-oleoyl Lysophosphatidic acid sodium promotes mitosis by inducing DNA synthesis.
M8994 AM095 free acid AM095 free acid is a potent LPA1 receptor antagonist which inhibited GTPγS binding to CHO cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73 μM, respectively.
M8993 BMS-986020 BMS-986020 (also known as AM152) is a potent and selective LPA1 antagonist.
M8992 AM966 AM966 is a potent, selective and orally active LPA(1) receptor antagonist which inhibits lung fibrosis in the mouse bleomycin model.
M7674 AM095 sodium AM095 is a potent and selective, orally bioavailable antagonist of lysophosphatidic acid receptor1 (LPA1).
M2213 Ki16425 Ki16425 is a LPA receptor antagonist with Ki values of 0.34, 6.5 and 0.93 μM for the human LPA1, LPA2 and LPA3 receptors, respectively.

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