| Cat.No. | Name | Information |
|---|---|---|
| M49409 | HL001 | HL001 is an LPA1 receptor antagonist that may be used in studies related to idiopathic pulmonary fibrosis (IPF). |
| M49408 | LTSE-2578 | LTSE-2578 is an LPA1 receptor antagonist that may be used in studies related to idiopathic pulmonary fibrosis (IPF). |
| M49407 | Fipaxalparant | Fipaxalparant is a potent, orally active and selective LPA1 receptor antagonist for studies related to idiopathic pulmonary fibrosis (IPF). |
| M43820 | EPGN-696 | EPGN-696 is an orally active LPA1 receptor antagonist for studies related to diabetic nephropathy and idiopathic pulmonary fibrosis. |
| M41859 | S1PR1 Radioligand 1 | S1PR1 Radioligand 1is a specific S1PR1 radioligand with IC50 = 8.7 nM. |
| M41858 | SLB1122168 | SLB1122168 is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. |
| M41857 | S1P1 agonist 6 | S1P1 agonist 6 is a S1P1 agonist that reduces autoimmune ability by blocking the transportation of lymphocytes. |
| M41856 | S1P1 agonist 6 hemicalcium | S1P1 agonist 6 hemicalcium is a S1P1 agonist that reduces autoimmune ability by blocking the transportation of lymphocytes. |
| M30823 | Ceralifimod | Ceralifimod (ONO-4641) is selective, high potent agonist for sphingosine 1-phosphate receptors 1 and 5, with EC50s of 27.3, 334 pM for human S1P receptor 1 and 5, respectively. |
| M30766 | CYM-5478 | CYM-5478 is a potent and highly selective S1P2 agonist with an EC50 of 119 nM in a TGFα-shedding assay. CYM-5478 protects neural-derived cell lines against Cisplatin toxicity. |
| M30208 | Mocravimod | Mocravimod is an oral activity amphematoshenol-1-1-phosphate receptor (S1PR) regulator, which can block the required signal from lymph organs to prevent the migration of effect cells from migrating to non-lymph hematopoietic tissue. Mocravimod can be used for cancer research. |
| M29817 | SLF1081851 TFA | SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (TFA) plays a key role in development and immune system. |
| M28982 | Udifitimod | Udifitimod (BMS-986166) is a potent, selective and orally active S1P1R modulator. Udifitimod has the potential for the research of autoimmune diseases. |
| M28326 | Ro 6842262 | Ro 6842262 (LPA1 receptor antagonist 1) is an orally bioavailable, highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist with an IC50 of 25 nM. Ro 6842262 attenuates NHLF human lung fibroblast cell proliferation and contraction in vitro. Ro 6842262 also reduces plasma histamine levels in mouse LPA-challenge model. |
| M28114 | ASP6432 | ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively. |
| M28004 | Siponimod hemifumarate | Siponimod (BAF-312) hemifumarate is a potent and selective sphingosine-1-phosphate (S1P) receptor modulator. Siponimod hemifumarate is selective for S1P1 and S1P5 receptors over S1P2, S1P3, and S1P4 (EC50s of 0.39, 0.98, >10000, >1000, and 750 nM, respectively). Siponimod hemifumarate can be used for multiple sclerosis (MS) research. |
| M21147 | GLPG2938 | GLPG2938 is a potent and selective S1P2 antagonist.GLPG2938 can be used in the study of idiopathic pulmonary fibrosis (IPF). |
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