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LHRH/GnRH Gonadotropin releasing hormone/Luteinizing hormone releasing hormone

Cat.No.  Name Information
M5735 Leuprolide Acetate Leuprolide acetate is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors.
M45271 Ganirelix acetate Ganirelix acetate is a competitive gonadotropin-releasing hormone (GnRH) antagonist that directly binds to endogenous molecules competing for the receptor and causes a rapid decrease in estradiol levels. Ganirelix acetate can be used in studies related to ovarian hyperstimulation syndrome (OHSS) and preterm labor.
M31385 Gonadorelin acetate Gonadorelin acetate is a decameric synthetic oligopeptide that is also a gonadotropin-releasing hormone (GnRH) agonist.
M31382 Triptorelin acetate Triptorelin acetate is a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) and a gonadotropin-releasing hormone (GnRH) agonist.
M30666 (R)-Elagolix Elagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM). Target: GnRH in vitro: Elagolix is a short-acting, nonpeptide, GnRH antagonist, administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. Elagolix is regarded as the frontrunner of a new class of GnRH inhibitors that have been denoted as second-generation, due to their non-peptide nature and oral bioavailability.
M22414 Buserelin Acetate Buserelin Acetate
M21021 Nafarelin Acetate Nafarelin Acetate is a Gonadotropin-releasing hormone (GnRH) agonist; synthetic decapeptide analog of GnRH (luteinizing hormone-releasing hormone, gonadorelin); structurally related to goserelin, leuprolide, and triptorelin.
M21020 Leuprorelin Leuprorelin is a natriuretic peptide analog of GnRH and a pituitary GnRH receptor agonist. It can be used in studies related to estrogen receptor (ER)-positive premenopausal breast cancer.
M13378 Antide Sequence:Ac-D2Nal-DCpa-DPal-Ser-Lys(nicotinoyl)-DLys(nicotinoyl)-Leu-Lys(isopropyl)-Pro-DAla-NH2
M13376 Abarelix Abarelix (R3827) is the first approved antagonist for the study of GnRH in advanced prostate cancer. Sequence:Ac-{d-2-Nal}-{d-4-Cpa}-{d-3-Pal}-S-{NMyr}-{d-Asp}-L-K(ipr)-P-{d-Ala}-NH2
M13375 Cetrorelix Acetate Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. Sequence:Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2
M13374 Ganirelix Sequence: Ac-D-2-Nal-D-Phe(4-Cl)-D-3-Pal-Ser-Tyr-D-Lys(C(NHEt)2)-Leu-Lys(C(NHEt)2)-Pro-D-Ala-NH2
M10505 Histrelin acetate Histrelin is a nonapeptide analog of GnRH (gonadotropin-releasing hormone) with added potency.
M10477 Linzagolix Linzagolix is a novel potent, orally active gonadotropin-releasing hormone (GnRH) antagonist.
M10250 Degarelix (GSK1278863) Degarelix (GSK1278863) is a third generation antagonist of luteinizing hormone-releasing hormone (LHRH, also termed gonadotropin-releasing hormone) for the first-line treatment of androgen-dependent advanced prostate cancer.
M9197 Relugolix Relugolix, also known as TAK-385, is an orally active gonadotropin-releasing hormone (GnRH) antagonist with an IC50 of 0.12 nM.
M5391 Alarelin Acetate Alarelin acetate is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions.
M5291 Sufugolix Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone LHRH receptor antagonist with an IC50 of 0.1 nM.
M1836 Deslorelin Acetate Deslorelin is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist.
M1835 Goserelin acetate Goserelin acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist.




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