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Histrelin is a nonapeptide analog of GnRH (gonadotropin-releasing hormone) with added potency. When present in the bloodstream, it can act on gonadotropes. Histrelin can stimulate these cells to release luteinizing hormone and follicle-stimulating hormone. Histrelin is considered a GnRH agonist. Histrelin acetate is used as a subcutaneous hydrogel implant for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
| Molecular Weight | 1383.58 |
| Formula | C66H86N18O12.XC2H4O2 |
| CAS Number | 220810-26-4 |
| Solubility (25°C) | Water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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