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Cat. No. M13378
Antide Structure
Size Price Availability Quantity
5mg USD 205  USD205 In stock
10mg USD 320  USD320 In stock
25mg USD 625  USD625 In stock
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Quality Control & Documentation
Biological Activity


Chemical Information
Molecular Weight 1591.29
Formula C82H108ClN17O14
CAS Number 112568-12-4
Solubility (25°C) N/A
Storage 2-8℃
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] C Derancourt, et al. Ann Dermatol Venereol. [Vaccinations]

[2] G Flouret, et al. J Pept Sci. Antiovulatory antagonists of LHRH related to antide

[3] K Gordon, et al. Biol Reprod. Antide-induced suppression of pituitary gonadotropin and ovarian steroid secretion in cynomolgus monkeys: premature luteolysis and prolonged inhibition of folliculogenesis following single treatment

[4] K Wallen, et al. Physiol Behav. Antide (Nal-Lys GnRH antagonist) suppression of pituitary-testicular function and sexual behavior in group-living rhesus monkeys

[5] M C Edelstein, et al. Contraception. Antide bioavailability: single dose administration for suppression of testosterone and inhibin in male monkeys

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