| Cat.No. | Name | Information |
|---|---|---|
| M25385 | Vialinin A | Vialinin A (Terrestrin A) is a potent inhibitor of ubiquitin-specific peptidases with IC50 values of 1.5, 5.9 and 22.3 μM for ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB), respectively. |
| M21141 | GNE-6640 | GNE-6640 is a selective, non-covalently bound inhibitor of ubiquitin-specific peptidase 7 (USP7) with IC50 values of 0.75 μM, 0.43 μM, 20.3 μM and 0.23 μM for USP7 full-length, USP7 catalytic domain, USP43 full-length and Ub-MDM2, respectively. |
| M13631 | MF-094 | MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy. |
| M13630 | HBX 19818 | HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM. |
| M13628 | EOAI3402143 | EOAI3402143 is a deubiquitinase (DUB) inhibitor, which inhibits dose-dependently inhibits Usp9x/Usp24 and Usp5. |
| M13626 | DUB-IN-2 | DUB-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8. |
| M13625 | DUB-IN-1 | DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs), with an IC50 of 0.85 μM for USP8. |
| M13390 | C527 | C527 is an inhibitor of pan-dub enzyme with an IC50 value of 0.88 μM. |
| M10753 | VLX1570 | VLX1570 is a competitive inhibitor of proteasome deuteronase (DUBs), with IC50 of 10 μM. |
| M10752 | GNE-6776 | GNE-6776 is a potent, selective USP7 inhibitor with oral activity. |
| M10751 | USP7-IN-8 | USP7-IN-8 is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in the Ub-Rho110 assay.USP7-IN-8 is inactive against USP47 and USP5.USP7-IN-8 has anticancer effects. |
| M10504 | IU1-47 | IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. |
| M9871 | GSK2643943A | GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor targeting USP20/Ub-Rho with an IC50 of 160 nM. |
| M9785 | ML364 | ML364 is a small molecule inhibitor of the deubiquitinase USP2 (IC50=1.1 μM) with potential anticancer activity. |
| M9654 | GRL0617 | GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro, with IC50 of 0.6 μM and Ki of 0.49 μM. |
| M9639 | SJB2-043 | Sjb2-043 inhibited USP1/UAF1 complex with IC50 of 544 nM. |
| M3052 | TCID | TCID is a DUB inhibitor for ubiquitin C-terminal hydrolase L3 with IC50 of 0.6 μM, 125-fold selective to L1. |
| M2807 | LDN-57444 | LDN-57444 is a reversible, competitive proteasome inhibitor for Uch-L1 with IC50 of 0.88 μM, 28-fold selectivity over isoform Uch-L3. |
| M2565 | PR-619 | PR-619 is a broad-spectrum reversible DUB (deubiquitinating enzyme) inhibitor of USP2, USP4, USP5, USP7 and USP8 with an EC50 of 3-9 μM. PR-619 also induces endoplasmic reticulum stress and endoplasmic reticulum stress-associated apoptosis. |
| M2431 | b-AP15 | b-AP15 is a deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage with IC50 of 2.1 μM. *The compound is unstable in solutions, freshly prepared is recommended |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
