| Cat.No. | Name | Information |
|---|---|---|
| M9639 | SJB2-043 | Sjb2-043 inhibited USP1/UAF1 complex with IC50 of 544 nM. |
| M6788 | HBX 41108 | HBX 41108 is a selective USP7 inhibitor with an IC50 of 424 nM. HBX 41108 inhibits USP7-mediated p53 deubiquitination to stabilize p53 and inhibits cancer cell growth. |
| M3052 | TCID | TCID is a DUB inhibitor for ubiquitin C-terminal hydrolase L3 with IC50 of 0.6 μM, 125-fold selective to L1. |
| M2807 | LDN-57444 | LDN-57444 is a reversible, competitive proteasome inhibitor for Uch-L1 with IC50 of 0.88 μM, 28-fold selectivity over isoform Uch-L3. |
| M2565 | PR-619 | PR-619 is a broad-spectrum reversible DUB (deubiquitinating enzyme) inhibitor of USP2, USP4, USP5, USP7 and USP8 with an EC50 of 3-9 μM. PR-619 also induces endoplasmic reticulum stress and endoplasmic reticulum stress-associated apoptosis. |
| M2431 | b-AP15 | b-AP15 is a deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage with IC50 of 2.1 μM. *The compound is unstable in solutions, freshly prepared is recommended |
| M2196 | P22077 | P22077 is a selective inhibitor of ubiquitin-specific protease (USP) 7 with EC50 of 8.6 μM. P 22077 also inhibits USP47 with an EC50 of 8.74 μM. |
| M2195 | P005091 | P005091 (P5091) is a potent and selective inhibitor of ubiquitin-specific protease (USP) 7 with IC50 of 4.2 μM. |
| M55952 | FT709 | FT709 is a potent and selective USP9X inhibitor, an IC50 of 82 nM. |
| M55951 | XL177A | XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM. |
| M55950 | LDN-91946 | LDN-91946 is a potent, selective and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM. |
| M55949 | USP5-IN-1 | USP5-IN-1, a potent deubiquitinase USP5 inhibitor, binds to the USP5 ZnF-UBD with a KD of 2.8 μM. |
| M50217 | TNG348 | TNG348 is a novel, oral, potent and selective ubiquitin-specific protease 1 (USP1) inhibitor for studies related to BRCA1/2 mutations and other homologous recombination defect (HRD)+ cancers. |
| M50216 | FT-3171 | FT-3171 is a small molecule ubiquitin-specific protease 1 (USP1) inhibitor targeting a novel DNA damage repair (DDR) pathway for studies related to solid tumors. |
| M49356 | BAY-728 | BAY-728 serves as a negative control for BAY-805, a potent and selective USP21 inhibitor. |
| M49355 | BAY-805 | BAY-805 is a selective inhibitor of the ubiquitin-specific protease USP21 with high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common off-target enzymes. |
| M41456 | USP1-IN-6 | USP1-IN-6 is a USP1 inhibitor (IC50<50 nM). |
| M41455 | USP1-IN-5 | USP1-IN-5 is a USP1 inhibitor (IC50<50 nM). |
| M41454 | CT1113 | CT1113 is a potent USP28 and USP25 inhibitor. |
| M41453 | GK13S | G13KS is a deubiquitinase UCHL1 ligand and inhibitor. |
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