Free shipping on all orders over $ 500

DUB-IN-1

Cat. No. M13625

All AbMole products are for research use only, cannot be used for human consumption.

DUB-IN-1 Structure
Size Price Availability Quantity
5mg USD 220  USD220 In stock
10mg USD 340  USD340 In stock
25mg USD 650  USD650 In stock
50mg USD 900  USD900 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs), with an IC50 of 0.85 μM for USP8.

Chemical Information
Molecular Weight 337.33
CAS Number 924296-18-4
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Beibei Sha, et al. Cell Biol Toxicol. USP8 inhibitor-induced DNA damage activates cell cycle arrest, apoptosis, and autophagy in esophageal squamous cell carcinoma

[2] Chia-Chuan Cho, et al. ChemMedChem. Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

Related Deubiquitinase Products
CMPD-39

CMPD-39 is a selective USP30 inhibitor with an IC50 of 0.02 μM. CMPD-39 increases protein ubiquitination and accelerates mitophagy.

FT709 

FT709 is a potent and selective USP9X inhibitor, an IC50 of 82 nM.

XL177A 

XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM.

LDN-91946 

LDN-91946 is a potent, selective and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM.

USP5-IN-1 

USP5-IN-1, a potent deubiquitinase USP5 inhibitor, binds to the USP5 ZnF-UBD with a KD of 2.8 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: DUB-IN-1 supplier, Deubiquitinase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.