Free shipping on all orders over $ 500

USP7/USP47 inhibitor 

Cat. No. M28037

All AbMole products are for research use only, cannot be used for human consumption.

USP7/USP47 inhibitor  Structure
Size Price Availability Quantity
5mg USD 110  USD110 In stock
10mg USD 190  USD190 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively.

Chemical Information
Molecular Weight 484.4
Formula C18H11Cl2N3O3S3
CAS Number 1247825-37-1
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kailing Pan, et al. Front Cell Dev Biol. Role of Ubiquitin-Specific Peptidase 47 in Cancers and Other Diseases

[2] Olof Engström, et al. Bioorg Med Chem Lett. Discovery of USP7 small-molecule allosteric inhibitors

[3] Pablo Palazón-Riquelme, et al. EMBO Rep. USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

[4] Jinhua Piao, et al. J Biochem. Expression, purification and enzymatic characterization of a recombinant human ubiquitin-specific protease 47

[5] Joseph Weinstock, et al. ACS Med Chem Lett. Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47

Related Deubiquitinase Products
CMPD-39

CMPD-39 is a selective USP30 inhibitor with an IC50 of 0.02 μM. CMPD-39 increases protein ubiquitination and accelerates mitophagy.

FT709 

FT709 is a potent and selective USP9X inhibitor, an IC50 of 82 nM.

XL177A 

XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM.

LDN-91946 

LDN-91946 is a potent, selective and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM.

USP5-IN-1 

USP5-IN-1, a potent deubiquitinase USP5 inhibitor, binds to the USP5 ZnF-UBD with a KD of 2.8 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: USP7/USP47 inhibitor  supplier, Deubiquitinase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.