| Cat.No. | Name | Information |
|---|---|---|
| M9638 | 4-Phenylbutyric acid (4-PBA) | 4-Phenylbutyric acid is an inhibitor of HDAC, inhibits the growth of NSCLC Cell Lines at 2 mM. |
| M6176 | TMP195 | TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays. |
| M5199 | Santacruzamate A | Santacruzamate A is a picomolar level selective inhibitor of HDAC2 with an IC50 of 85.8 nM, a Class I HDAC, with relatively little inhibition of HDAC4 or HDAC6, both Class II HDACs. |
| M4986 | LMK-235 | LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR). |
| M3988 | Sulforaphane | Sulforaphane (SFN) extracted from broccoli sprout is an agent with potent anti-oxidant and anti-inflammatory activity. |
| M3095 | Tubastatin A | Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). |
| M2977 | RGFP966 | RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC. |
| M2236 | CI-994 | CI-994 (N-acetyl dinaline, PD 123654) is a novel orally active HDAC inhibitor with IC50 of 0.57 μM for HDAC1. |
| M2101 | PCI-34051 | PCI-34051 is a potent histone deacetylase (HDAC) 8 inhibitor with IC50 of 0.01 μM. |
| M2007 | Romidepsin (FK228) | Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended |
| M1791 | Entinostat (MS-275) | Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively. |
| M1780 | Vorinostat | Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1. |
| M1753 | Trichostatin A | Trichostatin A (TSA) is a potent, reversible inhibitor of mammalian histone deacetylase (HDAC) with IC50 value around 20 nM. |
| M1748 | LBH589 (Panobinostat) | LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively. |
| M1742 | Tubacin | Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM. |
| M1738 | Niltubacin | Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6. |
| M49894 | Ac-Arg-Gly-Lys(Ac)-AMC acetate | Ac-Arg-Gly-Lys(Ac)-AMC acetate is a substrate for histone deacetylase (HDAC) and can be used in a novel fluorescent assay for HDAC activity. |
| M41495 | TNG260 | TNG260 is a CoREST-selective deacetylase (CoreDAC) inhibitor. |
| M40705 | Exifone | Exifone is an HDAC1 activator that binds free and substrate-bound enzyme, resulting in an increase in the relative maximum rate of HDAC1-catalyzed deacetylation. It can be used in studies related to memory dysfunction. |
| M13674 | CG347B | CG347B is a selective HDAC6 inhibitor. |
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