Free shipping on all orders over $ 500
  Catalog
Abmole Inhibitor Catalog 2017

HDAC Histone deacetylases

Inhibitors

Cat.No.  Name Information
M6073 WT161 WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM.
M6070 EDO-S101 EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively.
M5259 Citarinostat Citarinostat (ACY-241) is an orally available selective HDAC6 inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3.
M5200 BRD73954 BRD73954 ia a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.
M5152 Sodium Butyrate Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively.
M4986 LMK-235 LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR).
M4868 4SC-202 4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).
M3988 Sulforaphane Sulforaphane (SFN) extracted from broccoli sprout is an agent with potent anti-oxidant and anti-inflammatory activity.
M3979 Caffeic acid Caffeic acid is an endogenous phenolic phytochemical compound that exists in plants and many foods.
M3931 RGFP966 RGFP966 is a specific inhibitor of HDAC3 with an IC50 value of 0.08 μM and no effective inhibition of any other HDAC at concentrations up to 15 μM.
M3888 CAY10603 CAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM.
M3643 TMP269 TMP269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
M3405 AR-42 AR-42 is an HDAC inhibitor with IC50 of 30 nM.
M3395 M344 M344 is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.
M3243 Pyroxamide Pyroxamide (NSC 696085) is a potent, affinity-purified HDAC1 inhibitor with ID50 of 100 nM.
M3095 Tubastatin A Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
M3022 Sodium Phenylbutyrate Sodium Phenylbutyrate is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity.
M3002 Scriptaid Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3.
M2977 RGFP966 RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.
M2975 RG2833 RG2833 (RGFP109) is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.
M2878 Nexturastat A Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM, >190-fold selectivity over other HDACs.
M2400 Apicidin Apicidin is a potent nonselective HDAC inhibitor with IC50 of 0.7 nM.
M2236 CI-994 CI-994 (N-acetyl dinaline, PD 123654) is a novel orally active HDAC inhibitor with IC50 of 0.57 μM for HDAC1.
M2123 Rocilinostat Rocilinostat (ACY-1215) is an HDAC6-selective inhibitor with IC50 of 5 nM.
M2119 JNJ-26481585 JNJ-26481585 (Quisinostat) is a novel second-generation class I HDAC inhibitor.
M2111 CUDC-907 CUDC-907 is a potent, orally-available small molecule dual PI3K and HDAC inhibitor.
M2101 PCI-34051 PCI-34051 is a potent histone deacetylase (HDAC) 8 inhibitor with IC50 of 0.01 μM.
M2095 Resminostat Resminostat is a potent inhibitor of HDACs 1, 3 and 6 [50% inhibitory concentration (IC50)=43-72 nmol/l] representing HDAC classes I and II.
M2014 MC1568 MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor with IC50 of 220 nM.
M2007 Romidepsin Romidepsin (FK228) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.
M1993 Droxinostat Droxinostat is a selective inhibitor of HDAC3, HDAC6 and HDAC8 with IC50 of 16.9 μM, 2.47μM and 1.46 μM, respectively.
M1876 Valproic acid sodium salt Valproic acid (VPA) is a histone deacetylase inhibitor which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels.
M1813 PCI-24781 PCI-24781 is a novel and potent histone deacetylase (HDAC) inhibitor with IC50 value of 0.43 to 2.7 μM.
M1791 MS-275 MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM).
M1790 MGCD0103 MGCD0103 is a novel HDAC inhibitor, highly specific for classes I and IV HDACs, with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3 respectively.
M1780 Vorinostat Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1.
M1778 SB939 SB939 is a novel potent and orally active histone deacetylase with high tumor exposure and efficacy in mouse models of colorectal cancer.
M1775 Tubastatin A hydrochloride Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 values of 15 nM.
M1753 Trichostatin A Trichostatin A (TSA) is a potent, reversible inhibitor of mammalian histone deacetylase (HDAC) with IC50 value around 20 nM.
M1748 LBH589 LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively.
M1747 LAQ824 LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase (HDAC) inhibitor with an IC50 of 0.032 μM.
M1742 Tubacin Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM.
M1738 Niltubacin Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6.
M1730 ITF2357 ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively.
M1722 CHR-3996 CHR-3996 is an orally bioavailable, second-generation hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
M1708 EX 527 EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with an IC50 of 38 nM.
M1693 CUDC-101 CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively.
M1670 Belinostat Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM.


Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.