About 15 results found for searched term "Thalidomide" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2225 | Thalidomide | Ligand for E3 Ligase |
| Thalomid | ||
| Thalidomide is a sedative and immunomodulator used to study the symptoms of many cancers, it has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM. | ||
| M8797 | (+)-Thalidomide | Others |
| (-)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor α (TNF-α). | ||
| M9832 | E3 ligase Ligand 2 | Ligand for E3 Ligase |
| Thalidomide-4-OH; Cereblon ligand 2 | ||
| E3 ligase Ligand 2 (Thalidomide-4-OH) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it can be connected to the ligand for protein by a linker to form PROTACs. | ||
| M9833 | E3 ligase Ligand 3 | Ligand for E3 Ligase |
| Thalidomide-O-COOH; Cereblon ligand 3 | ||
| E3 ligase Ligand 3 (Thalidomide-O-COOH) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it connected to the ligand for protein by a linker to form PROTACs. | ||
| M9834 | E3 ligase Ligand 4 | Ligand for E3 Ligase |
| Thalidomide 4-fluoride | ||
| E3 ligase Ligand 4 (Thalidomide 4-fluoride) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it can connect to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1. | ||
| M9837 | Thalidomide-O-amido-C4-NH2 (TFA) | E3 Ligase Ligand-Linker Conjugates |
| Cereblon Ligand-Linker Conjugates 6 TFA | ||
| Thalidomide-O-amido-C4-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. | ||
| M10387 | Thalidomide-NH-CH2-COOH | Ligand for E3 Ligase |
| Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. | ||
| M14861 | Thalidomide-O-amido-C8-NH2 TFA | PROTAC |
| Cereblon Ligand -Linker Conjugates 2 TFA; E3 Ligase Ligand-Linker Conjugates 20 TFA | ||
| Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | ||
| M22448 | Thalidomide-NH-PEG3-propionic acid | PROTAC |
| Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. | ||
| M29226 | Thalidomide-O-amido-C4-N3 | PROTAC |
| Cereblon Ligand-Linker Conjugates 4; E3 ligase Ligand-Linker Conjugates 18 | ||
| Thalidomide-O-amido-C4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | ||
| M30423 | Thalidomide-5-OH | Ligand for E3 Ligase |
| Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs. | ||
| M31272 | Thalidomide-C2-amido-C2-COOH | E3 Ligase Ligand-Linker Conjugates |
| Thalidomide-C2-amido-C2-COOH incorporates a CRBN ligand for the E3 ubiquitin ligase, and a linker. Thalidomide-C2-amido-C2-COOH can be used to design PROTAC CDK2/9 Degrader-1. | ||
| M31273 | Thalidomide-NH-PEG2-C2-NH-Boc | E3 Ligase Ligand-Linker Conjugates |
| Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a PEG linker used for dBRD9 synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology. | ||
| M43412 | Tz-Thalidomide | Epigenetic Reader Domain |
| Tz-Thalidomide is a tetrazine tagged Thalidomide. | ||
| M43418 | Thalidomide-5-propargyl | Ligand for E3 Ligase |
| Thalidomide-5-propargyl is a propargyl-modified Thalidomide, that acts as a Cereblon ligand to recruit CRBN proteins. | ||
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