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E3 ligase Ligand 3 (Thalidomide-O-COOH) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it connected to the ligand for protein by a linker to form PROTACs.
Molecular Weight | 332.26 |
Formula | C15H12N2O7 |
CAS Number | 1061605-21-7 |
Solubility (25°C) | DMSO 35 mg/mL |
Storage | 2-8°C, dry, sealed |
[1] Mikołaj Słabicki, et al. Small-molecule-induced polymerization triggers degradation of BCL6
[2] Kalliopi Tzavlaki, et al. TGF-β Signaling
[4] Jun Araya, et al. PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis
Related Ligand for E3 Ligase Products |
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