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(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-enantiomer of Thalidomide.
| Molecular Weight | 258.23 |
| Formula | C13H10N2O4 |
| CAS Number | 841-67-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage | 4°C, protect from light |
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ALV1 is a molecular glue degrader for Ikaros (IKZF1) and Helios (IKZF2) with DC50 of 2.5 nM and 10.3 nM respectively. ALV1 bind CRBN with an IC50 of 0.55 μM, and induces CRBN-Helios dimerization. |
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