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E3 ligase Ligand 2

Cat. No. M9832

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E3 ligase Ligand 2 Structure
Synonym:

Thalidomide-4-OH; Cereblon ligand 2

Size Price Availability Quantity
50mg USD 180  USD180 In stock
100mg USD 300  USD300 In stock
500mg USD 900  USD900 In stock
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Quality Control & Documentation
Biological Activity

E3 ligase Ligand 2 (Thalidomide-4-OH) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it connected to the ligand for protein by a linker to form PROTACs.

Chemical Information
Molecular Weight 274.23
Formula C13H10N2O5
CAS Number 5054-59-1
Solubility (25°C) DMSO 30 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Megan G Marks, et al. Biol Pharm Bull. Effects of putative hydroxylated thalidomide metabolites on blood vessel density in the chorioallantoic membrane (CAM) assay and on tumor and endothelial cell proliferation

Related Ligand for E3 Ligase Products
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2,6-Bis(benzyloxy)pyridine-3-boronic acid

2,6-Bis(benzyloxy)pyridine-3-boronic acid

2,6-Bis(benzyloxy)-3-bromopyridine

2,6-Bis(benzyloxy)-3-bromopyridine

2,6-bis(benzyloxy)pyridin-3-amine

2,6-bis(benzyloxy)pyridin-3-amine

3-[2,5-Difluoro-4-(4-piperidinyl)phenyl]-2,6-piperidinedione

3-[2,5-Difluoro-4-(4-piperidinyl)phenyl]-2,6-piperidinedione

  Catalog
Abmole Inhibitor Catalog




Keywords: E3 ligase Ligand 2, Thalidomide-4-OH; Cereblon ligand 2 supplier, Ligand for E3 Ligase, inhibitors, activators

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