About 6 results found for searched term "TPh A" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8816 | TPh A | Others |
| TPh A is an inhibitor of the nuclear protein pirin. | ||
| M3538 | Telotristat Etiprate | Tryptophan Hydroxylase |
| LX 1606 Hippurate | ||
| Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. | ||
| M14542 | LX-1031 | Tryptophan Hydroxylase |
| LX-1031 is a potent, orally available tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin (5-HT) synthesis peripherally. | ||
| M21499 | Rodatristat ethyl | Others |
| KAR5585 | ||
| Rodatristat ethyl (KAR5585) was a first-in-class inhibitor of tryptophan hydroxylase 1 (TPH1) with oral activity. | ||
| M28796 | Rodatristat | 5-HT Receptor |
| KAR5417 | ||
| Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice. | ||
| M28854 | ACT-678689 | Tryptophan Hydroxylase |
| ACT-678689 (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM. | ||
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