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ACT-678689 (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM.
| Molecular Weight | 565.04 |
| Formula | C23H22ClFN6O4S2 |
| CAS Number | 1783256-96-1 |
| Solubility (25°C) | DMSO 125 mg/mL (ultrasonic) |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Related Tryptophan Hydroxylase Products |
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| Telotristat
Telotristat (LP-778902) is a potent tryptophan hydroxylase inhibitor with an in vivo IC50 of 0.028 μM. |
| LX-1031
LX-1031 is a potent, orally available tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin (5-HT) synthesis peripherally. |
| Telotristat ethyl
Telotristat ethyl, also known as LX1606, is an oral serotonin synthesis inhibitor or peripheral tryptophan hydroxylase (TPH) inhibitor. |
| Telotristat Etiprate
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. |
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