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TPh A

Cat. No. M8816

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TPh A Structure

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Quality Control & Documentation
Biological Activity

TPh A is an inhibitor of the nuclear protein pirin. TPh A (Triphenyl compound A) inhibits the interaction between Bcl3 oncoprotein and the nuclear protein pirin. TPh A inihibits melanoma cell migration.

Chemical Information
Molecular Weight 399.53
Formula C21H21NO3S2
CAS Number 21306-65-0
Solubility (25°C) DMSO: ≥30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Vanessa S Wacleche, et al. Identification of T Peripheral Helper (Tph) Cells

[2] Dan-Qian Chen, et al. Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription

[3] Hiroyuki Yoshitomi, et al. Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases

[4] Hayato Yabe, et al. Cytotoxic Tph-like cells are involved in persistent tissue damage in IgG4-related disease

[5] Thelma Beatriz Gonzlez-Castro, et al. Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis

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Keywords: TPh A supplier, inhibitors, activators

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