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Rodatristat ethyl

Cat. No. M21499

All AbMole products are for research use only, cannot be used for human consumption.

Rodatristat ethyl Structure
Synonym:

KAR5585

Size Price Availability Quantity
5mg USD 920  USD920 In stock
10mg USD 1450  USD1450 In stock
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Quality Control & Documentation
Biological Activity

Rodatristat ethyl (KAR5585) was a first-in-class inhibitor of tryptophan hydroxylase 1 (TPH1) with oral activity.

Chemical Information
Molecular Weight 590.04
Formula C29H31ClF3N5O3
CAS Number 1673571-51-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Howard M Lazarus, et al. Pulm Circ. A trial design to maximize knowledge of the effects of rodatristat ethyl in the treatment of pulmonary arterial hypertension (ELEVATE 2)

[2] David F Condon, et al. Chest. Novel Mechanisms Targeted by Drug Trials in Pulmonary Arterial Hypertension

[3] Daniel R Goldberg, et al. Bioorg Med Chem Lett. Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors

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Keywords: Rodatristat ethyl, KAR5585 supplier, inhibitors, activators

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