About 30 results found for searched term "SOD" (0.003 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1847 | Fostamatinib disodium | Syk |
| R788 Disodium; R-935788 Disodium | ||
| Fostamatinib disodium (R788, R-935788) is a potent, ATP-competitive and selective Syk (Spleen tyrosine kinase) inhibitor with IC50 of 41 nM. | ||
| M1868 | NXY-059 | Others |
| Disufenton sodium, Cerovive | ||
| NXY-059 is a free radical-trapping neuroprotectant that has been reported to reduce infarct size and preserve brain function in experimental models of acute ischemic stroke. | ||
| M1876 | Valproic acid sodium salt | HDAC |
| Sodium valproate | ||
| Valproic acid (VPA) is a histone deacetylase inhibitor which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels. | ||
| M1960 | Bicalutamide | Androgen Receptor |
| Casodex, Cosudex | ||
| Bicalutamide is an orally active non-steroidal androgen receptor antagonist (IC50 = 190 nM). | ||
| M2029 | Sitaxsentan sodium | Endothelin Receptor |
| TBC-11251 | ||
| Sitaxsentan (TBC-11251) is an orally active, highly selective antagonist of endothelin A receptors. | ||
| M2034 | Pemetrexed disodium | Antifolate |
| Alimta, LY231514 disodium | ||
| Pemetrexed is a novel antifolic acid antimetabolic compound with K I of 1.3 nM, 7.2 nM, and 65 nM for TS, DHFR, and GARFT, respectively. | ||
| M2126 | Fluvastatin sodium | HMG-CoA Reductase |
| XU 62-320 | ||
| Fluvastatin sodium is an orally active, potent and competitive HMG-CoA reductase inhibitor with IC50 value between 40 and 100 nM at human liver microsomes. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. | ||
| M2211 | Rigosertib sodium | PLK |
| ON-01910 sodium; CAS# 592542-60-4 | ||
| Rigosertib sodium is a dual non-ATP inhibitor of polo-like kinase 1 (Plk1) and phosphoinositide 3-kinase pathways (PI3K). | ||
| M2250 | Pamidronate disodium | Others |
| Aredia | ||
| Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. | ||
| M2273 | Clodronate disodium | Others |
| Clodronate disodium is the disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. | ||
| M2274 | Fosbretabulin disodium | Microtubule |
| Combretastatin A-4 phosphate, CA4P | ||
| Fosbretabulin disodium (Combretastatin A-4 phosphate) is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM. | ||
| M2594 | Montelukast sodium | IL Receptor/Related |
| Montelukast sodium selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1. | ||
| M2382 | Amfenac Sodium Monohydrate | Others |
| Amfenac sodium H2O | ||
| Amfenac Sodium monohydrate is a non-steroidal analgesic anti-inflammatory compound with acetic acid moiety. | ||
| M2390 | Ampicillin sodium | Antibiotic |
| D-(-)-α-Aminobenzylpenicillin sodium salt | ||
| Ampicillin is a beta-lactam antibiotic that is part of the aminopenicillin family. | ||
| M2427 | Azlocillin sodium salt | Antibiotic |
| Sodium azlocillin | ||
| Azlocillin is an acylampicillin with a broad spectrum against bacteria. | ||
| M2429 | Balsalazide disodium | Sirtuin |
| Balsalazide is an anti-inflammatory compound used to study inflammatory bowel disease and ulcerative colitis. | ||
| M2471 | Bromfenac Sodium | COX |
| Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. | ||
| M2475 | Bucladesine Sodium Salt | PKA |
| Dibutyryl-cAMP sodium salt; DC2797; Sodium dibutyryl cAMP | ||
| Bucladesine, a membrane permeable selective activator of PKA, has a critical role in up-regulation of ChAT and VAChT gene expression in PC12 cells by activation of extracellular signal regulated kinase (ERK) in Ca2+- and PKA-dependent manner. | ||
| M2491 | Carbenicillin disodium | Plant growth regulators |
| Sodium carbenicillin | ||
| Carbenicillin is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity. | ||
| M2492 | Carbenoxolone Sodium | Hydroxysteroid dehydrogenase |
| Carbenoxolone, a synthetic derivative of glycyrrhetinic acid, is also used as a blocker of the enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD), of pannexon membrane channels (comprising 6 subunits of pannexin) and the related innexon channels. | ||
| M2535 | Closantel Sodium | Anti-infection |
| Closantel is gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM. | ||
| M2626 | Dexamethasone Sodium Phosphate | Animal Modeling |
| Dexamethasone phosphate disodium | ||
| Dexamethasone Sodium Phosphate is a glucocorticoid receptor agonist that induces the production of lipocortin, a phospholipase A2 inhibitory protein. Dexamethasone inhibits autophagy levels in damaged cells in a dose-dependent manner. It can be used to construct models of allergic conjunctivitis. | ||
| M2635 | Dicloxacillin Sodium | Antibiotic |
| Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria. | ||
| M2662 | Efaproxiral Sodium | ROS |
| RSR13; NSC722758 | ||
| Efaproxiral Sodium is a synthetic allosteric modifier of hemoglobin, used for brain metastases originating from breast cancer. | ||
| M2713 | Foscarnet Sodium | Others |
| Phosphonoformate | ||
| Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs. | ||
| M2763 | Ibandronate sodium | Apoptosis |
| Ibandronate sodium is a potent nitrogen-containing bisphosphonate that can be used in studies related to osteoporosis. | ||
| M2815 | Liothyronine Sodium | Others |
| T3 Sodium salt; Sodium L-3,3',5-triiodothyronine; Liothyronine sodium | ||
| Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. | ||
| M2817 | Meclofenamate sodium | COX |
| CI 583 ; Meclofenamic acid sodium | ||
| Meclofenamate sodium is a dual COX-1/COX-2 inhibitor with an IC50 of 40 nM and 50 nM, respectively. used in the study of joint and muscle pain, arthritis, and dysmenorrhea. meclofenamate sodium is a non-selective gap-junction blocker and a highly selective inhibitor of adipose and obesity-associated enzyme (FTO) inhibitor. | ||
| M2848 | Mezlocillin Sodium | Antibiotic |
| Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. | ||
| M2865 | Sodium Monofluorophosphate | Pyruvate Kinase |
| Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM. | ||
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