About 12 results found for searched term "SE 175" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8161 | SE 175 | Others |
| An organic nitrate compound that acts as an NO donor in vivo following reductive transformation of the nitrate group to nitric oxide. | ||
| M1800 | JNJ-7706621 | CDK |
| JNJ7706621 | ||
| JNJ-7706621 is a dual cell cycle inhibitor with activity against cyclin-dependent kinases (CDK1, 2, 3, 6) with an IC50 of 3-175 nM and Aurora kinases (A and B) with an IC50 of 11-15 nM respectively. | ||
| M8906 | Sematilide hydrochloride | Potassium Channel |
| CK-1752 hydrochloride | ||
| Sematilide (CK-1752) hydrochloride is a novel class III antiarrhythmic agent. | ||
| M10600 | SAH-SOS1A TFA | Ras |
| SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106-175 nM) and directly and independently blocks nucleotide association. | ||
| M14435 | PF429242 dihydrochloride | FAS |
| PF429242 dihydrochloride is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with an IC50 of 175 nM. | ||
| M28392 | GSK8175 | Anti-infection |
| GSK2878175 | ||
| GSK8175 is a non-nucleoside polymerase (NS5B) inhibitor of hepatitis C virus (HCV). GSK8175 is a sulfonamide- N-benzoxaborole analog with low in vivo clearance across preclinical species and broad-spectrum activity against HCV replicons. | ||
| M29605 | ANT3310 sodium | Antibiotic |
| ANT3310 sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). ANT3310 sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). ANT3310 sodium can be used in the research of bacterial infection. | ||
| M30723 | LT175 | PPAR |
| LT175, a dual PPARα/γ ligand, is an orally active partial agonist against PPARγ(hPPARα:EC50=0.22 μm; mPPARα:EC50=0.26 μm; hPPARγ:EC50=0.48 μm). LT175 interacts with PPARγ and affects the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1 (NCoR1). LT175 interacts with PPARγ in a hydrophobic region called “diphenyl pocket”. LT175 has potent insulin-sensitizing effects and reduced adipogenic properties. | ||
| M31206 | Bisindolylmaleimide VIII acetate | PKC |
| Ro 31-7549 acetate; Bis VIII acetate | ||
| Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively. | ||
| M41213 | TSC26 | Parasite |
| TSC26, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 175 nM, a pIC50 of 6.76 and a pKa of 6.6. | ||
| M54205 | Hemokinin 1 (mouse) | Neurokinin Receptor |
| Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively. | ||
| M58408 | CM-1758 | HDAC |
| CM-1758 is a histone deacetylase (HDAC) inhibitor. CM-1758 inhibits tumor growth in vivo. CM-1758 induces acetylation of non-histone proteins in acute myeloid leukemia cells. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
