About 12 results found for searched term "RO495" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20744 | RO495 | JAK |
| CS-2667 | ||
| RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2). | ||
| M2542 | CTEP | GluR |
| mGluR5 inhibitor | ||
| CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors. | ||
| M11153 | Phalloidin | Fluorescent Dye |
| Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome (λex=495 nm, λem=520 nm). | ||
| M11520 | Acridine Orange 10-Nonyl Bromide | Fluorescent Dye |
| Nonylacridine orange | ||
| Acridine Orange 10-nonyl Bromide is a fluorescent probe binding to cardiolipin in mitochondria. The ranging wavelength is 495 nm/521nm. Storage at room temperature and away from light. | ||
| M21464 | FITC-Dextran (MW 10000) | Fluorescent Dye |
| FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption. | ||
| M24642 | Landogrozumab | Others |
| LY2495655; Anti-GDF8Myostatin Reference Antibody | ||
| Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease. | ||
| M25053 | Isecarosmab | Others |
| M-6495 | ||
| Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life. | ||
| M28062 | PF-4950834 | ROCK |
| PF-4950834 is a potent, selective, orally bioavailable, ATP-competitive rho kinase inhibitor with IC50 values of 8.35 nM and 33.12 nM against ROCK2 and ROCK1, respectively. PF-4950834 inhibits neutrophil migration. | ||
| M39115 | (-)-Cyclopenol | Metabolite/Endogenous Metabolite |
| (-)-Cyclopenol is a fungal metabolite isolated from an Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) . | ||
| M40799 | 1,3-Diphenylisobenzofuran | Fluorescent Dye |
| DPBF | ||
| 1,3-Diphenylisobenzofuran is a selective fluorescent probe that reacts highly specifically with a number of reactive oxygen species (e.g., singlet oxygen and hydroxyl, alkyl oxygen, or alkyl peroxy radicals), and can be used for the quantitative detection of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS), (λex=495 nm, λem=523 nm). | ||
| M53539 | CEF20 | Anti-infection |
| CEF20 is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503). | ||
| M58202 | Hoechst S 769121 | Fluorescent Dye |
| Nuclear yellow | ||
| Hoechst S 769121 (Nuclear yellow) is a DNA-selective dye that is used to label DNA content in live and fixed cells. Upon binding to DNA, nuclear yellow fluoresces, and this fluorescence can be measured using fluorescence microscopy, microplate fluorometry, or flow cytometry. Nuclear yellow displays excitation/emission maxima of 355/495 nm, respectively. | ||
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