About 8 results found for searched term "Notch" (0.101 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1746 | DAPT | Gamma-secretase/Beta-secretase |
| GSI-IX | ||
| DAPT (GSI-IX) is a γ-secretase inhibitor with IC50 values of 115 and 200 nM for total Aβ and Aβ42 respectively. DAPT inhibits the activation of Notch 1 signaling. | ||
| M14574 | Notch inhibitor 1 | Notch |
| BMS-986115 | ||
| Notch inhibitor 1 is a potent inhibitor of Notch, with IC50 values of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively.In addition, Notch inhibitor 1 is also an inhibitor of gamma-secretase, which can be used in sclerofibrosarcoma-related studies. | ||
| M24627 | Tarextumab | Notch |
| OMP 59R5; Anti-Human NOTCH2 Recombinant Antibody | ||
| Tarextumab (OMP-59R5) is an anti-Notch2/3 fully human IgG2 monoclonal antibody. Tarextumab shows anti-tumor activity. | ||
| M24681 | Brontictuzumab | Notch |
| OMP 52M51; Anti-Human NOTCH1 Recombinant Antibody | ||
| Brontictuzumab (OMP 52M51) is a monoclonal antibody (MAb) that inhibits Notch1 signal. Brontictuzumab selectively binds the negative regulatory region of the Notch1. Brontictuzumab inhibits tumor cell proliferation. Brontictuzumab can be used in the research of leukemia and lymphoma. | ||
| M59885 | NOTCH1 Mouse Pre-designed siRNA Set | siRNA |
| Mouse NOTCH1 Pre-designed siRNA Set contains three designed siRNAs for NOTCH1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 18128 | ||
| M61341 | notch2 Human Pre-designed siRNA Set | siRNA |
| Human notch2 Pre-designed siRNA Set contains three designed siRNAs for notch2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 4853 | ||
| M63636 | NOTCH1 Human Pre-designed siRNA Set | siRNA |
| Human NOTCH1 Pre-designed siRNA Set contains three designed siRNAs for NOTCH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 4851 | ||
| M64907 | NOTCH3 Human Pre-designed siRNA Set | siRNA |
| Human NOTCH3 Pre-designed siRNA Set contains three designed siRNAs for NOTCH3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 4854 | ||
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