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Notch inhibitor 1 is a potent inhibitor of Notch, with IC50 values of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively.In addition, Notch inhibitor 1 is also an inhibitor of gamma-secretase, which can be used in sclerofibrosarcoma-related studies.
Molecular Weight | 574.49 |
CAS Number | 1584647-27-7 |
Solubility (25°C) | DMSO 10 mg/mL |
Storage | 2-8°C, sealed |
[3] Timothy M Smith Jr, et al. Targeting ADAM10 in Cancer and Autoimmunity
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