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Procyanidin B2 3,3'-di-O-gallate

Cat. No. M39205

All AbMole products are for research use only, cannot be used for human consumption.

Procyanidin B2 3,3'-di-O-gallate Structure

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Quality Control & Documentation
Biological Activity

Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway.

Chemical Information
Molecular Weight 882.73
Formula C44H34O20
CAS Number 79907-44-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Katsunori Endo et al. Eur J Pharmacol. Oral administration of procyanidin B2 3,3"-di-O-gallate ameliorates experimental autoimmune encephalomyelitis through immunosuppressive effects on CD4+ T cells by regulating glycolysis

[2] Toko Sawa et al. Int Immunopharmacol. Procyanidin B2 3,3''-di-O-gallate ameliorates imiquimod-induced skin inflammation by suppressing TLR7 signaling through the inhibition of endosomal acidification in dendritic cells

[3] Katsunori Endo et al. Int Immunopharmacol. Procyanidin B2 3,3″-di-O-gallate suppresses IFN-γ production in murine CD4+ T cells through the regulation of glutamine influx via direct interaction with ASCT2

[4] Alpna Tyagi et al. Mol Carcinog. Differential effect of grape seed extract and its active constituent procyanidin B2 3,3″-di-O-gallate against prostate cancer stem cells

[5] Rahul Kumar et al. Mol Carcinog. Procyanidin B2 3,3″-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK

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Keywords: Procyanidin B2 3,3'-di-O-gallate supplier, Notch, inhibitors, activators

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