All AbMole products are for research use only, cannot be used for human consumption.
RBPJ Inhibitor-1 (RIN1) is a first-in-class RBPJ inhibitor that blocks the interaction between RBPJ and SHARP.RBPJ Inhibitor-1 (RIN1) inhibits the proliferation of Notch-dependent tumor cells.
| Molecular Weight | 311.31 |
| Formula | C17H14FN3O2 |
| CAS Number | 2682114-39-0 |
| Form | Solid |
| Solubility (25°C) | DMSO > 120 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Notch Products |
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| Jagged-1 (188-204)
Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. |
| DAPM
DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. |
| Procyanidin B2 3,3'-di-O-gallate
Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway. |
| SAHM1 TFA
SAHM1 TFA is a Notch pathway inhibitor. SAHM1 TFA stabilizes hydrocarbon-stapled alpha helical peptide. SAHM1 TFA targets the protein-protein interface and prevents Notch complex assembly. |
| JI051
JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity. |
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Products are for research use only. Not for human use. We do not sell to patients.
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