About 20 results found for searched term "NOD-IN-1" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2857 | Nodinitib-1 | NLR |
| ML130; CID-1088438 | ||
| Nodinitib-1 (ML130) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2. | ||
| M7547 | NOD-IN-1 | NLR |
| NOD2- | ||
| NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively. | ||
| M3381 | Nevirapine | Reverse Transcriptase |
| BI-RG 587; NSC 641530; NVP | ||
| Nevirapine (NSC 641530) is a potent, specific non-nucleoside reverse transcriptase inhibitor (NNRTIs) that non-competitively inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with a Ki of 220 nM. Nevirapine (NSC 641530) can be used in AIDS-related researchs. | ||
| M6650 | Daminozide | Histone demethylase |
| DaminoDaminozide is a plant growth regulator and selective inhibitor of human KDM2/7 histone demethylases, with IC50 values of 0.55, 1.5, and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively.Daminozide is >100-fold selective for KDM2/7 demethylases compared to other demethylase subfamily members tested. zide is a selective KDM2/7 inhibitor. | ||
| M9272 | S107 | Others |
| S107 free base | ||
| S107 is a Type 1 ryanodine receptor (RyR1) stabilizer. | ||
| M17749 | Ganodermanontriol | Triterpenoids |
| Ganodermanontriol is a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. | ||
| M18527 | Ganoderic acid DM | Apoptosis |
| Ganoderic acid DM is a natural triterpenoid isolated from Ganoderma lucidum, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Ganoderic acid DM as a specific inhibitor of osteoclastogenesis. | ||
| M18578 | Ganoderic acid TR | Anti-infection |
| Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases with IC50 values of 10.9 and 4.6 μM, respectively. | ||
| M19174 | Halleridone | Keap1-Nrf2 |
| Halleridone is a natural product isolated from Halleria lucida (Scrophulariaceae), Teucrium decipiens, Phyla nodiflora and the stems of the plant Cornus walteri. Halleridone activated Nrf2-mediated HO-1 expression and inhibited Aβ1-42-overexpressed microglial BV-2 cell activation. | ||
| M28539 | Ganoderic acid AM1 | Others |
| GAAM1 | ||
| Ganoderic acid AM1 (GAAM1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid AM1 shows cytotoxicity with an IC50 value of 19.8 µM for HeLa cells. | ||
| M28756 | JH-VIII-157-02 | ALK |
| JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells. | ||
| M28968 | JE-2147 | HIV Protease |
| AG1776; KNI-764 | ||
| JE-2147 (AG1776) is a potent dipeptide protease inhibitor with a Ki of 0.33 nM for HIV-1 protease. JE-2147 has effective activities against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro. | ||
| M30183 | Chlorantraniliprole | Others |
| Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM). | ||
| M30463 | Formycin A | HIV Protease |
| NSC 102811 | ||
| Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities. | ||
| M30733 | Ganoderic acid Y | Glucosidase |
| Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating. | ||
| M38629 | Lucialdehyde B | Antibiotic |
| Lucialdehyde B is a tetracyclic triterpene isolated from the substrates of Ganoderma lucidum with antiviral and cytotoxic activities. Lucialdehyde B has cytotoxic effects against Lewis lung cancer (LLC), T-47D, Sarcoma 180 and Meth-A tumor cell lines. | ||
| M40417 | Epinodosin | Others |
| Epinodosin is a diterpenoid. Epinodosin has moderate cytotoxicity against HL-60 cells with IC50 value of 10.4 μM. Epinodosin can be used for the research of inflammatory diseases. | ||
| M51519 | KSPWFTTL | Others |
| KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. | ||
| M52798 | Maurocalcine | Calcium Channel |
| Maurocalcine is an agonist of ryanodine receptor (RyR) channel types 1, 2 and 3 with cellular permeability. | ||
| M54031 | HSV-gB2 (498-505) | Anti-infection |
| HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope. | ||
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