Formycin A

Cat. No. M30463

All AbMole products are for research use only, cannot be used for human consumption.

Synonym:

NSC 102811

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation

Purity: ≥99.0%
COA
MSDS

Product Information

Biological Activity

Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities.

Chemical Information

Molecular Weight	267.24
Formula	C10H13N5O4
CAS Number	6742-12-7
Form	Solid
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Meng Zhang, et al. Appl Environ Microbiol. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds

[2] Shao-An Wang, et al. J Am Chem Soc. Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis

[3] Małgorzata Prokopowicz, et al. Biochimie. A synergistic effect of phosphate, pH and Phe159 substitution on the formycin A association to the E. coli purine nucleoside phosphorylase

[4] B Kierdaszuk, et al. Biochim Biophys Acta. Formycin A and its N-methyl analogues, specific inhibitors of E. coli purine nucleoside phosphorylase (PNP): induced tautomeric shifts on binding to enzyme, and enzyme-->ligand fluorescence resonance energy transfer

[5] D Ochi, et al. J Antibiot (Tokyo). Biosynthesis of formycin. Formation of formycin from formycin B

Related HIV Protease Products
Ritonavir-13c,d3 Ritonavir-13c,d3
Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease.
Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 is a substrato peptídico of HIV-1 protease.
HIV-1, HIV-2 Protease Substrate HIV-1, HIV-2 Protease Substrate is the substrate of HIV-1, HIV-2 protease.
HIV Protease Substrate IV HIV Protease Substrate IV is a substrate of HIV protease.

Catalog

By Signaling Pathways

By Product Type

Signaling Pathways

Formycin A

NSC 102811

Price and Availability

Quality Control & Documentation

Biological Activity

Chemical Information

References

Get to Know Us

Customer Support

Resources

Contact Us