About 16 results found for searched term "NA-17" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3272 | Alendronate sodium hydrate | Others |
| Alendronate; MK 217; G-704650 Adronat | ||
| Alendronate is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM. | ||
| M5035 | Clascoterone | Androgen Receptor |
| CB-03-01; clascoterone; Cortexolone 17 alpha-propionate; Cortexolone 17α-propionate | ||
| Clascoterone (Cortexolone 17α-propionate, CB-03-01) is a new selective androgen receptor (AR) antagonist. | ||
| M5477 | Carbazochrome sodium sulfonate (AC-17) | Adrenergic Receptor |
| AC-17 | ||
| Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for use in the treatment of hemorrhoids. | ||
| M8605 | NA-17 | Others |
| NA-17 is a fluorescent naphthalimide that induces accumulation of activated p53 in mitochondria and nuclei of NSCLC cells. | ||
| M13371 | Onametostat (JNJ-64619178) | PRMTs |
| Onametostat (JNJ-64619178) is a highly selective, orally active, pseudo-irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor (PRMT5-MEP-50, IC50=0.14 nM).Onametostat does not covalently bind to PRMT5, but has a long interaction time. It has good pharmacokinetic properties as well as safety profile. | ||
| M15033 | Recombinant Mouse IL-17A (CHO) | Cytokines and Growth Factors |
| IL17A, CTLA-8 | ||
| Interleukin-17a (also known as CTLA-8) is a pleiotropic cytokine expressed by T cells and has a high degree of homology to the protein encoded by the ORF13 gene of herpetic virus squirrel monkey. Protein structure: IL-17A (ALA26-ALA158), Accession # Q62386. | ||
| M20456 | Carbazochrome | Others |
| Adedolon, Adchnon, Adrenostazin, Cromadrenal, Adona, AC-17 | ||
| Carbazochrome is a hemostatic agent that causes the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. | ||
| M21556 | Recombinant Human IL-17A (E.coli) | Cytokines and Growth Factors |
| Interleukin-17A; IL-17; IL-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8 | ||
| Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. Recombinant human interleukin 17a is produced by the Escherichia coli expression system and expresses the target gene encoding Gly24-Ala155. | ||
| M21705 | Recombinant Mouse IL-17F (HEK293, C-6His) | Cytokines and Growth Factors |
| Interleukin-17F | ||
| Recombinant Mouse Interleukin-17F is produced by Mammalian expression system and the target gene encoding Arg29-Ala161 is expressed with a 6His tag at the C-terminus. Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. | ||
| M21706 | Recombinant Human IL-17F (HEK293, C-6His) | Cytokines and Growth Factors |
| Interleukin-17F human | ||
| Recombinant Human Interleukin-17F is produced by Mammalian expression system and the target gene encoding Arg31-Gln163 is expressed with a 6His tag at the C-terminus. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. | ||
| M21723 | Recombinant Human IL-17F (HEK293) | Cytokines and Growth Factors |
| Interleukin-17F | ||
| Recombinant Human Interleukin-17F is produced by our Mammalian expression system and the target gene encoding Arg31-Gln163 is expressed. IL-17F can stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. The ED50 of Human IL-17F is 24.21 ng/ml. | ||
| M25299 | Citatuzumab bogatox | Apoptosis |
| VB6-845; Anti-Human EpCAM Recombinant Antibody Fab Fragment, 17-1A | ||
| Citatuzumab bogatox (VB6-845) is recombinant immunotoxin that composed of Fab fragment of humanized antibody targeting EpCAM and a modified cytotoxin bouganin. Citatuzumab bogatox binds to and selectively induces apoptosis in EpCAM-positive cell lines and shows good activity in EpCAM-positive human tumour xenograft models. | ||
| M45121 | Recombinant Human IL-17B (HEK293, C-Fc) | Cytokines and Growth Factors |
| interleukin-17 beta | ||
| Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. | ||
| M55381 | Recombinant Human IL-25/IL-17E (HEK293, C-6His) | Cytokines and Growth Factors |
| Interleukin-25; Interleukin-17E | ||
| Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. | ||
| M55382 | Recombinant Human IL-25/IL-17E (E. coli, C-His) | Cytokines and Growth Factors |
| Interleukin-25; Interleukin-17E | ||
| Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. | ||
| M55644 | Recombinant Human CDH17 Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| Cadherin-17 | ||
| Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherin-17 plays a role in the morphological organization of liver and intestine and involved in intestinal peptide transport. | ||
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