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Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherin-17 plays a role in the morphological organization of liver and intestine and involved in intestinal peptide transport. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells.
Recombinant Human Cadherin-17/CDH17 expressed the target gene encoding Gln23-Met787 with a 6His tag at the C-terminus.
Immobilized Recombinant Human CDH17 (C-6His) at 2 μg/ml (100 μl/well) can bind Anti-Human Cadherin-17 mab, the ED50 of Anti-Human Cadherin-17 mab is 7.34 ng/ml.
Accession AAI13465.1
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 110-130 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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