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 About 12 results found for searched term "Guanine" (0.051 seconds)

Cat.No.  Name Target
M2414 Azaguanine-8 Others
Azaguanine-8 is a purine analogs showing antineoplastic activity by competing with guanine in the metabolism.
M3258 Thioguanine DNA/RNA Synthesis
6-Thioguanine; 6-TG; 2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol
Thioguanine is a purine antimetabolite widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.
M5332 NU2058 CDK
NU-2058; O6-(Cyclohexylmethyl)guanine
NU2058 is a guanine-based CDK inhibitor with IC50 of 17 μM and 26 μM for CDK2 and CDK1.
M8703 8-Aminoguanine Others
8-amino-guanine, a guanine derivative, is an orally effective potassium-preserving diuretic/sodium compound that increases sodium excretion 17.
M13473 2-(Methylamino)-1H-purin-6(7H)-one Antibiotic
2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids.
M13646 Guanine DNA/RNA Synthesis
Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
M13651 O6-Benzylguanine DNA/RNA Synthesis
O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor.
M13698 5-Aza-7-deazaguanine Others
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides.
M14340 2'-Deoxyguanosine Metabolite/Endogenous Metabolite
Deoxyguanosine; Guanine deoxyriboside
2'-Deoxyguanosine (Deoxyguanosine) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
M38939 6-Chloroguanineriboside Nucleoside Antimetabolite/Analog
6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
M38941 Isoguanine Nucleoside Antimetabolite/Analog
Isoguanine is a purine base that is an isomer of Guanine. A building block in organic synthesis.
M42929 9-Deazaguanine Others
9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP).

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