About 13 results found for searched term "Guanine" (0.038 seconds)
Cat.No. | Name | Target |
---|---|---|
M2414 | Azaguanine-8 | Others |
Azaguanine-8 is a purine analogs showing antineoplastic activity by competing with guanine in the metabolism. | ||
M3258 | Thioguanine | DNA/RNA Synthesis |
6-Thioguanine; 6-TG; 2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol | ||
Thioguanine is a purine antimetabolite widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients. | ||
M5332 | NU2058 | CDK |
NU-2058; O6-(Cyclohexylmethyl)guanine | ||
NU2058 is a guanine-based CDK inhibitor with IC50 of 17 μM and 26 μM for CDK2 and CDK1. | ||
M8703 | 8-Aminoguanine | Others |
8-amino-guanine, a guanine derivative, is an orally effective potassium-preserving diuretic/sodium compound that increases sodium excretion 17. | ||
M13473 | 2-(Methylamino)-1H-purin-6(7H)-one | Antibiotic |
N2-methylguanine | ||
2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids. | ||
M13646 | Guanine | DNA/RNA Synthesis |
Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. | ||
M13651 | O6-Benzylguanine | DNA/RNA Synthesis |
O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. | ||
M13698 | 5-Aza-7-deazaguanine | Others |
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides. | ||
M14340 | 2'-Deoxyguanosine | Metabolite/Endogenous Metabolite |
Deoxyguanosine; Guanine deoxyriboside | ||
2'-Deoxyguanosine (Deoxyguanosine) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. | ||
M38939 | 6-Chloroguanineriboside | Nucleoside Antimetabolite/Analog |
6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | ||
M38941 | Isoguanine | Nucleoside Antimetabolite/Analog |
Isoguanine is a purine base that is an isomer of Guanine. A building block in organic synthesis. | ||
M42929 | 9-Deazaguanine | Others |
9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP). | ||
M56646 | 8-Hydroxyguanine hydrochloride | Metabolite/Endogenous Metabolite |
8-Hydroxyguanine hydrochloride is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. |
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