About 18 results found for searched term "Apelin Receptor" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10097 | Apelin-13 TFA | Apelin Receptor |
| Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. | ||
| M10197 | (Glp1)-Apelin-13 human, bovine | Apelin Receptor |
| [Pyr1]-Apelin-13 | ||
| (Glp1)-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. | ||
| M10208 | Apelin-36(rat, mouse) TFA | Apelin Receptor |
| Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. | ||
| M14810 | Elabela(19-32) | Apelin Receptor |
| Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. | ||
| M14811 | Elabela(19-32) TFA | Apelin Receptor |
| Elabela(19-32) TFA is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) TFA activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) TFA induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. | ||
| M20849 | (Ala13)-Apelin-13 | Others |
| (Ala13)-Apelin-13 is a potent APJ receptor antagonist and can prevent the apelin-induced reduction in gastric tone and motility. | ||
| M21380 | MM 07 | Others |
| MM 07 is a biased apelin receptor agonist with a KD value of 300 nM in CHO-K cells and 172 nM in human heart. | ||
| M28632 | CMF019 | Others |
| CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. | ||
| M29134 | Azelaprag | Others |
| AMG 986 | ||
| Azelaprag (Example 263.0) is an apelin receptor agonist agent candidate. | ||
| M53106 | Apelin-17(human, bovine) | Others |
| Apelin-17(human, bovine) is an endogenous orphan G protein-coupled receptor APJ agonist. | ||
| M53258 | Apelin-13 | Apelin Receptor |
| Apelin-13 is an endogenous ligand for the G-protein coupled receptor angiotensin II protein J (APJ), activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. | ||
| M53259 | ELA-32(human) | Others |
| ELA-32 (human) is a potent critical cardiac developmental peptide that acts through the G-protein–coupled apelin receptor. | ||
| M54245 | Apelin-12 | Anti-infection |
| Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. | ||
| M54274 | ELA-11(human) | Others |
| ELA-11(human), a peptide, is a full agonist of human apelin receptor, with a pKi of 7.85. | ||
| M54302 | ELA-21 (human) | Others |
| ELA-21 (human) is an apelin receptor agonist with a pKi of 8.52. | ||
| M54471 | Apelin-36(human) | Others |
| Apelin-36(human) is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. | ||
| M54482 | Apelin-36(rat, mouse) | Others |
| Apelin-36(rat, mouse) is an endogenous orphan G protein-coupled receptor APJ agonist. | ||
| M55030 | ML339 | CXCR |
| ML-339 | ||
| ML339 is a selective CXCR6 antagonist with an IC50 of 140 nM. ML339 has no inhibitory effect on CXCR5, CXCR4 and apelin receptor (APJ). | ||
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