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Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM.
Neurochem Int. 2024 Oct 19;Nov:180:105885.
Apelin regulates mitochondrial dynamics by inhibiting Mst1-JNK-Drp1 signaling pathway to reduce neuronal apoptosis after spinal cord injury
Apelin-13 TFA purchased from AbMole
| Molecular Weight | 1664.85 |
| Formula | C71H112F3N23O18S |
| CAS Number | 217082-58-1 (free base) |
| Solubility (25°C) | Water 90 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Apelin Receptor Products |
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| Apelin-13
Apelin-13 is an endogenous ligand for the G-protein coupled receptor angiotensin II protein J (APJ), activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. |
| Elabela(19-32) TFA
Elabela(19-32) TFA is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) TFA activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) TFA induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. |
| Elabela(19-32)
Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. |
| Apelin-36(rat, mouse) TFA
Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. |
| (Glp1)-Apelin-13 human, bovine
(Glp1)-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. |
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