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Elabela(19-32) TFA is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) TFA activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) TFA induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart.
| Molecular Weight | 1821.05 |
| Formula | C77H120F3N25O19S2 |
| CAS Number | 1886973-05-2 (free base) |
| Solubility (25°C) | DMSO 90 mg/mL Water 30 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
| Related Apelin Receptor Products |
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| Apelin-13
Apelin-13 is an endogenous ligand for the G-protein coupled receptor angiotensin II protein J (APJ), activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. |
| Elabela(19-32)
Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. |
| Apelin-36(rat, mouse) TFA
Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. |
| (Glp1)-Apelin-13 human, bovine
(Glp1)-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. |
| Apelin-13 TFA
Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. |
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