About 17 results found for searched term "Aldehyde dehydrogenase" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M55218 | Aldehyde dehydrogenase | Enzymes & Coenzymes |
| ALDH | ||
| Aldehyde dehydrogenase is a soluble enzyme and its activity depends on potassium ions and cysteine. ALDH is a component of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH) recycling systems. | ||
| M58510 | Recombinant Mouse GAPDH Protein (E. coli, N-His) | Cytokines and Growth Factors |
| Glyceraldehyde 3-phosphate dehydrogenase; G3PDH | ||
| GAPDH is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. GAPDH may be genetically associated with late-onset of Alzheimer's disease. | ||
| M58533 | Recombinant Human GAPDH Protein (E. coli, C-His) | Cytokines and Growth Factors |
| Glyceraldehyde 3-phosphate dehydrogenase; G3PDH | ||
| GAPDH is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. GAPDH may be genetically associated with late-onset of Alzheimer's disease. | ||
| M3390 | Disulfiram | Pyroptosis |
| Tetraethylthiuram disulfide; TETD | ||
| Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1). Disulfiram is used in the study of chronic alcoholism, with acute sensitivity to alcohol, and is a potent copper ion-carrier that can be used in cuproptosis studies. | ||
| M4152 | Daidzin | Dehydrogenase |
| Daidzoside; NPI-031D; Daidzein 7-O-glucoside | ||
| Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone. | ||
| M6423 | Alda-1 | ALDH |
| Alda1 | ||
| Alda-1 is a potent and selective Aldehyde Dehydrogenase-2 Agonist. Alda-1 activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2. | ||
| M8290 | Aldi-2 | Others |
| Aldi-2 is a potent and specific covalent inhibitor of aldehyde dehydrogenases. | ||
| M8781 | NCT-501 | ALDH |
| NCT-501 is a potent and selective inhibitor of Aldehyde dehydrogenase ALDH1A1, a dehydrogenase that has been found to be elevated in certain cancers and in cancer stem cells. | ||
| M16813 | Prunetin | ALDH |
| Prunetin is an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. | ||
| M20485 | Phenylglyoxal hydrate | Dehydrogenase |
| 1-Phenylethanedione hydrate | ||
| Phenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties. | ||
| M20768 | CM10 | ALDH |
| CM10 is a potent and selective inhibitor of aldehyde dehydrogenase 1A family (ALDH1A) with IC50 of 1700 nM, 740 nM and 640 nM for ALDH1A1, ALDH1A2 and ALDH1A3, respectively. CM10 exhibits anti-cancer activity. | ||
| M25461 | Misetionamide | Apoptosis |
| Misetionamide is an orally glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with antineoplastic activity. | ||
| M29205 | EN40 | ALDH |
| EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM. | ||
| M31093 | RV01 | ALDH |
| RV01 is a novel quinolyl-substituted analogue of resveratrol, it inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol. RV01 exhibits hydroxyl radical scavenging activity. | ||
| M43198 | Tri-valine | Others |
| Tri-valine (NSC 35938) is a polypeptide that can be separated from Creatine kinase, β-enolase, Triosephosphate isomerase and glyceraldehyde 3-phosphate dehydrogenase. | ||
| M43936 | ADX-104 | RASP |
| ADX-104 is a Reactive Aldehyde Substance (RASP) inhibitor that can be used in studies related to succinate semialdehyde dehydrogenase deficiency disease. | ||
| M58106 | NCT-505 | ALDH |
| NCT505 | ||
| NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM. NCT-505 weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57, 22.8, 20.1, >57 μM, respectively. | ||
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