Phenylglyoxal hydrate

Cat. No. M20485

All AbMole products are for research use only, cannot be used for human consumption.

Synonym:

1-Phenylethanedione hydrate

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Quality Control & Documentation

Purity: >99%
COA
MSDS

Product Information

Biological Activity

Phenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.

Chemical Information

Molecular Weight	152.15
Formula	C8H8O3
CAS Number	1075-06-5
Solubility (25°C)	DMSO 30 mg/mL
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Bahgat R M Hussein, et al. Mol Divers. Utility of arylglyoxal hydrates in synthesis of 4-aroyl-[1,3,5]triazino[1,2-a]benzimidazol-2(1H)-imines and 5-aryl-2-phenyl-4H-imidazol-4-imines

[2] Jiangyao Chen, et al. Chemosphere. Atomic-level insight into effect of substrate concentration and relative humidity on photocatalytic degradation mechanism of gaseous styrene

[3] Beata Żołnowska, et al. Molecules. Novel 5-Substituted 2-(Aylmethylthio)-4-chloro-N-(5-aryl-1,2,4-triazin-3-yl)benzenesulfonamides: Synthesis, Molecular Structure, Anticancer Activity, Apoptosis-Inducing Activity and Metabolic Stability

[4] Swapna Konda, et al. J Org Chem. Organocatalyzed asymmetric aldol reactions of ketones and β,γ-unsaturated α-ketoesters and phenylglyoxal hydrates

[5] O D Radnoff, et al. Proc Soc Exp Biol Med. Inhibition of Hageman factor, plasma thromboplastin antecedent, thrombin and other clotting factors by phenylglyoxal hydrate (38500)

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MTHFD2-IN-3 MTHFD2-IN-3 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor.
MTHFD2-IN-2 MTHFD2-IN-2 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor.
MTHFD2-IN-1 MTHFD2-IN-1 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor.

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Phenylglyoxal hydrate

1-Phenylethanedione hydrate

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