| Cat.No. | Name | Information |
|---|---|---|
| M31314 | D-Lactate dehydrogenase | D-Lactate dehydrogenase is an oxidoreductase widely found in bacteria and fungi that acts on donor CH-OH groups using NAD+ or NADP+ as an acceptor and also catalyzes the oxidation of D-lactate to pyruvate. |
| M31174 | Alcohol dehydrogenase | Alcohol dehydrogenase is a dimerization protein present in cells that catalyzes the reversible reduction of carbonyl groups to their corresponding alcohols. |
| M31108 | Olorofim | Olorofim is an orally active, novel dihydroorotic acid dehydrogenase inhibitor that also targets pyrimidine biosynthesis in mycobacteria and has antifungal activity. |
| M14724 | LY 345899 | LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1. |
| M10085 | Mycophenolate mofetil | Mycophenolate mofetil is an inhibitor of inosine monophosphate dehydrogenase (IMPDH). |
| M8472 | BVT 2733 | BVT 2733 is a potent, selective, and orally active non-steroidal 11β-hydroxydehydrogenase 1 (11β-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM). |
| M6034 | Trilostane | Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome. |
| M5663 | Fomepizole | Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites. |
| M5202 | Exherin (ADH-1) | ADH-1 (Exherin) is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. *The compound is unstable in solutions, freshly prepared is recommended |
| M4930 | SW033291 | SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. |
| M4152 | Daidzin | Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone. |
| M3721 | ML323 | Ml-323 is a potent reversible INHIBITOR of USP1-UAF1, with an IC50 of 76 nM in UB-RHO assay. |
| M2563 | NSC 14613 | NSC 14613 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs. |
| M2297 | Devimistat (CPI-613) | Devimistat (CPI-613) inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase. |
| M42500 | MTHFD2-IN-4 | MTHFD2-IN-4, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. |
| M42499 | MTHFD2-IN-4 sodium | MTHFD2-IN-4 sodium, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. |
| M42498 | MTHFD2-IN-3 | MTHFD2-IN-3 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor. |
| M42497 | MTHFD2-IN-2 | MTHFD2-IN-2 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor. |
| M42496 | MTHFD2-IN-1 | MTHFD2-IN-1 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor. |
| M42275 | HSD17B13-IN-3 | HSD17B13-IN-3 is a potent hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor. |
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