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Dehydrogenase Dehydrogenase

Cat.No.  Name Information
M31314 D-Lactate dehydrogenase D-Lactate dehydrogenase is an oxidoreductase widely found in bacteria and fungi that acts on donor CH-OH groups using NAD+ or NADP+ as an acceptor and also catalyzes the oxidation of D-lactate to pyruvate.
M31174 Alcohol dehydrogenase Alcohol dehydrogenase is a dimerization protein present in cells that catalyzes the reversible reduction of carbonyl groups to their corresponding alcohols.
M31108 Olorofim Olorofim is an orally active, novel dihydroorotic acid dehydrogenase inhibitor that also targets pyrimidine biosynthesis in mycobacteria and has antifungal activity.
M14724 LY 345899 LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1.
M10085 Mycophenolate mofetil Mycophenolate mofetil is an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
M8472 BVT 2733 BVT 2733 is a potent, selective, and orally active non-steroidal 11β-hydroxydehydrogenase 1 (11β-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM).
M6034 Trilostane Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.
M5663 Fomepizole Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
M5202 Exherin (ADH-1) ADH-1 (Exherin) is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. *The compound is unstable in solutions, freshly prepared is recommended
M4930 SW033291 SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.
M4152 Daidzin Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.
M3721 ML323 Ml-323 is a potent reversible INHIBITOR of USP1-UAF1, with an IC50 of 76 nM in UB-RHO assay.
M2563 NSC 14613 NSC 14613 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs.
M2297 Devimistat (CPI-613) Devimistat (CPI-613) inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase.
M42500 MTHFD2-IN-4 MTHFD2-IN-4, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor.
M42499 MTHFD2-IN-4 sodium MTHFD2-IN-4 sodium, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor.
M42498 MTHFD2-IN-3 MTHFD2-IN-3 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor.
M42497 MTHFD2-IN-2 MTHFD2-IN-2 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor.
M42496 MTHFD2-IN-1 MTHFD2-IN-1 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor.
M42275 HSD17B13-IN-3 HSD17B13-IN-3 is a potent hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor.

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