About 30 results found for searched term "ACE" (0.002 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1689 | BTZ043 Racemate | Anti-infection |
| BTZ038, BTZ044 | ||
| BTZ043 Racemate (BTZ038, BTZ044) is a decaprenylphosphoryl-b-D-ribose 2-epimerase inhibitor. | ||
| M1742 | Tubacin | HDAC |
| Tubulin Acetylation Inducer | ||
| Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM. | ||
| M1835 | Goserelin acetate | LHRH/GnRH |
| ICI-118630 acetate | ||
| Goserelin acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist. | ||
| M1836 | Deslorelin Acetate | LHRH/GnRH |
| H 4065 | ||
| Deslorelin is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. | ||
| M1860 | AT-101 | Bcl-2 |
| R-(-)-gossypol acetic acid | ||
| AT-101 (R-(-)-gossypol acetic acid) is a pan small molecule inhibitor of Bcl-2, Bcl-xL, and Mcl-1. | ||
| M1947 | BMS-708163 | Gamma-secretase/Beta-secretase |
| Avagacestat | ||
| BMS-708163 (Avagacestat) is a selective γ-secretase inhibitor (IC50 = 0.3 nM). | ||
| M2142 | Anacetrapib | CETP |
| MK-0859 | ||
| Anacetrapib is an orally active and potent inhibitor of CETP with IC50 of 7.9 nM and 11.8 nM for rhCETP and mutant CETP(C13S) respectively. | ||
| M2164 | PD 123319 ditrifluoroacetate | Angiotensin Receptor |
| PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. | ||
| M2226 | Melatonin | Melatonin Receptor |
| Melatonex; N-Acetyl-5-methoxytryptamine; MT | ||
| Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. | ||
| M2236 | CI-994 | HDAC |
| Tacedinaline, PD 123654 | ||
| CI-994 (N-acetyl dinaline, PD 123654) is a novel orally active HDAC inhibitor with IC50 of 0.57 μM for HDAC1. | ||
| M2243 | Aniracetam | AChR/AChE |
| Draganon, Sarpul | ||
| Aniracetam is a compound that promotes intellectual development and neuroprotection. | ||
| M2257 | Levetiracetam | AChR/AChE |
| Keppra; UCB L059 | ||
| Levetiracetam (UCB L059) is an antiepileptic, it is also a selective M2 muscarinic acetylcholine receptors (mAChR) inhibitor. | ||
| M2277 | Semagacestat | Gamma-secretase/Beta-secretase |
| LY450139 | ||
| Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, respectively. | ||
| M2330 | Evacetrapib | CETP |
| LY2484595 | ||
| Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP which inhibited human recombinant CETP protein (5.5 nM IC(50)) and CETP activity in human plasma (36 nM IC(50)) in vitro. | ||
| M2365 | Acebutolol hydrochloride | Adrenergic Receptor |
| Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. | ||
| M2366 | Aceclidine hydrochloride | AChR/AChE |
| Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure. | ||
| M2367 | Acesulfame K | Others |
| Acesulfame potassium is a non-nutritive sweetener. | ||
| M2619 | Deoxycorticosterone acetate | Animal Modeling |
| DOCA; 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate | ||
| Deoxycorticosterone acetate, an adrenocorticotropic hormone and also a precursor of aldosterone, as well as a salicorticoid receptor (MR) agonist, can be used to construct rat models of hypertension. | ||
| M2625 | Dexamethasone acetate | Animal Modeling |
| Dexamethasone 21-acetate | ||
| Dexamethasone acetate is a potent glucocorticoid-like synthetic that inhibits the pituitary-adrenal axis. It can be used to construct animal models of atopic dermatitis. | ||
| M2629 | Diacerein | Others |
| Diacerhein; Diacetylrhein; Fisiodar; Artrodar | ||
| Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis. | ||
| M2641 | Diminazene Aceturate | Anti-infection |
| Diminazene is a di-amidine also known as 4,4-(1-Triazene-1,3-diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. | ||
| M2692 | Ethynodiol diacetate | Progesterone Receptor |
| Ethynodiol acetate | ||
| Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills. | ||
| M2709 | Fluorometholone Acetate | Carbonic Anhydrase |
| Fluorometholone Acetate is a synthetic corticosteroid and a potent carbonic anhydrase (CA) inhibitor with IC50s of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It has anti-inflammatory activity and may be used in studies related to steroid-responsive ocular inflammation. | ||
| M2738 | Guanabenz Acetate | Adrenergic Receptor |
| WY-8678 Acetate; GBZ Acetate | ||
| Guanabenz Acetate is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively. | ||
| M2827 | LY3039478 | Gamma-secretase/Beta-secretase |
| Crenigacestat | ||
| LY3039478 (Crenigacestat) is a novel and orally active Notch and γ-secretase inhibitor, with an IC50 of 1 nM in most of the tumor cell lines tested. | ||
| M2938 | Phthalylsulfacetamide | Antibiotic |
| Benzenesulfonamide is a sulfonamide compound with high solubility, suitable for systemic use in eye diseases. | ||
| M2949 | Piracetam | GABA Receptor |
| Piracetam is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. | ||
| M3037 | Sulfacetamide Sodium | Antibiotic |
| Sulfacetamide Sodium is an anti-biotic. | ||
| M3073 | Tiratricol | Thyroid Hormone Receptor |
| 3,3',5-Triiodothyroacetic acid | ||
| Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue. | ||
| M3232 | Cortisone acetate | Animal Modeling |
| Cortisone 21-acetate | ||
| Cortisone acetate is the acetate form of Cortisone, a steroid hormone and glucocorticoid that suppresses the immune system, thereby reducing inflammatory pain and swelling at the site of injury.Cortisone acetate and epinephrine, the primary hormones released by the body in response to stress, elevate blood pressure. They can be used to construct animal models of hypertension. | ||
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